Electrochemical SNPs detection using an abasic site-containing DNA on a gold electrode

An abasic site-containing DNA combined with lumiflavin allows amperometric determination of single nucleotide polymorphism through hydrogen bond-mediated nucleobase recognition in water by using abasic sites as a molecular recognition field.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2006-01 (22), p.2376-2378
Hauptverfasser: Morita, Kotaro, Sankaran, N B, Huang, Weimin, Seino, Takehiro, Sato, Yusuke, Nishizawa, Seiichi, Teramae, Norio
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container_end_page 2378
container_issue 22
container_start_page 2376
container_title Chemical communications (Cambridge, England)
container_volume
creator Morita, Kotaro
Sankaran, N B
Huang, Weimin
Seino, Takehiro
Sato, Yusuke
Nishizawa, Seiichi
Teramae, Norio
description An abasic site-containing DNA combined with lumiflavin allows amperometric determination of single nucleotide polymorphism through hydrogen bond-mediated nucleobase recognition in water by using abasic sites as a molecular recognition field.
doi_str_mv 10.1039/b517391d
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source MEDLINE; Royal Society of Chemistry Journals Archive (1841-2007); Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Base Pairing
Binding Sites
DNA - chemistry
Electrochemistry
Electrodes
Flavins - chemistry
Gold - chemistry
Hydrogen Bonding
Ligands
Polymorphism, Single Nucleotide
Surface Properties
Water - chemistry
title Electrochemical SNPs detection using an abasic site-containing DNA on a gold electrode
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