Differential expression of inducible nitric oxide synthase and IL-12 between peritoneal and splenic macrophages stimulated with LPS plus IFN-γ is associated with the activation of extracellular signal-related kinase

Resident peritoneal macrophages (pMϕ) are found deficient in T cell-stimulating capacity compared with the competent splenic macrophages (sMϕ). Macrophages (Mϕ)-derived nitric oxide (NO) and IL-12 have been shown to play crucial roles in the interaction between Mϕ and T cells. To further understand...

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