Strategies for increasing the sensitivity of gadolinium based MRI contrast agents

Gadolinium(III) complexes are often used in clinical MRI to increase contrast by selectively relaxing the water molecules near the complex. There is a desire to improve the sensitivity (relaxivity) of these contrast agents in order to detect molecular targets. This tutorial review describes the mole...

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Veröffentlicht in:	Chemical Society reviews 2006-01, Vol.35 (6), p.512-523
1. Verfasser:	Caravan, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Contrast Media - chemistry Gadolinium - chemistry Magnetic Resonance Imaging - methods Models, Molecular Molecular Structure Organometallic Compounds - chemistry Sensitivity and Specificity
Online-Zugang:	Volltext
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