Inhibitory Effects of Lutein on Endotoxin-Induced Uveitis in Lewis Rats

Lutein deposits in the macula and lens of human eyes with high concentration and is well known as an eye-protective nutrient for its beneficial effects on eye disease such as age-related macular degeneration and cataract. The purpose of the present study was to investigate the effects of lutein on e...

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Veröffentlicht in:	Investigative ophthalmology & visual science 2006-06, Vol.47 (6), p.2562-2568
Hauptverfasser:	Jin, Xue-Hai, Ohgami, Kazuhiro, Shiratori, Kenji, Suzuki, Yukari, Hirano, Takeshi, Koyama, Yoshikazu, Yoshida, Kazuhiko, Ilieva, Iliyana, Iseki, Ken, Ohno, Shigeaki
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents, Non-Steroidal - pharmacology Aqueous Humor - metabolism Biological and medical sciences Blotting, Western Cell Line Ciliary Body - drug effects Ciliary Body - metabolism Cyclooxygenase 2 - metabolism Cytokines - metabolism Disease Models, Animal Dose-Response Relationship, Drug Eye and associated structures. Visual pathways and centers. Vision Fundamental and applied biological sciences. Psychology I-kappa B Proteins - metabolism Iris - drug effects Iris - metabolism Lipopolysaccharides Lutein - pharmacology Macrophages - metabolism Male Medical sciences Mice Microscopy, Confocal NF-kappa B - metabolism Nitric Oxide Synthase Type II - metabolism Ophthalmology Rats Rats, Inbred Lew Salmonella typhimurium Uvea diseases Uveitis, Anterior - metabolism Uveitis, Anterior - prevention & control Vertebrates: nervous system and sense organs
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