In vitro efficacy of a whitening toothpaste containing calcium carbonate and perlite
The studies described in this paper aimed to assess the stain removal efficacy, fluoride efficacy and abrasivity to enamel and dentine of a new whitening toothpaste containing calcium carbonate and perlite, using appropriate in vitro models. Stain removal efficacy was assessed using the pellicle cle...
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| Veröffentlicht in: | International dental journal 2005, Vol.55 (3 Suppl 1), p.197-202 |
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| container_issue | 3 Suppl 1 |
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| container_title | International dental journal |
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| creator | Pickles, M J Evans, M Philpotts, C J Joiner, A Lynch, R J M Noel, N Laucello, M |
| description | The studies described in this paper aimed to assess the stain removal efficacy, fluoride efficacy and abrasivity to enamel and dentine of a new whitening toothpaste containing calcium carbonate and perlite, using appropriate in vitro models.
Stain removal efficacy was assessed using the pellicle cleaning ratio (PCR) method. Fluoride efficacy was assessed using remineralisation, demineralisation and fluoride-uptake methods. Abrasivity was assessed using an enamel and dentine wear method.
The results showed that the new whitening toothpaste was able to remove extrinsic tooth stain more effectively than three commercially available toothpaste formulations. The fluoride efficacy was superior to a non-fluoridated control and was not significantly different to a clinically tested fluoride-containing toothpaste. The abrasivity data showed that the calcium carbonate/perlite toothpaste is no more abrasive to enamel or dentine than two other commercially available whitening toothpastes.
The studies show that the new whitening toothpaste is effective in extrinsic stain removal, has an efficacious fluoride source and does not have an undue degree of abrasivity to enamel or dentine compared to other relevant commercially available products. |
| doi_str_mv | 10.1111/j.1875-595x.2005.tb00060.x |
| format | Article |
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Stain removal efficacy was assessed using the pellicle cleaning ratio (PCR) method. Fluoride efficacy was assessed using remineralisation, demineralisation and fluoride-uptake methods. Abrasivity was assessed using an enamel and dentine wear method.
The results showed that the new whitening toothpaste was able to remove extrinsic tooth stain more effectively than three commercially available toothpaste formulations. The fluoride efficacy was superior to a non-fluoridated control and was not significantly different to a clinically tested fluoride-containing toothpaste. The abrasivity data showed that the calcium carbonate/perlite toothpaste is no more abrasive to enamel or dentine than two other commercially available whitening toothpastes.
The studies show that the new whitening toothpaste is effective in extrinsic stain removal, has an efficacious fluoride source and does not have an undue degree of abrasivity to enamel or dentine compared to other relevant commercially available products.</description><identifier>ISSN: 0020-6539</identifier><identifier>DOI: 10.1111/j.1875-595x.2005.tb00060.x</identifier><identifier>PMID: 16004254</identifier><language>eng</language><publisher>England</publisher><subject>Aluminum Oxide - therapeutic use ; Animals ; Anti-Infective Agents, Local - therapeutic use ; Calcium Carbonate - therapeutic use ; Cariostatic Agents - pharmacokinetics ; Cariostatic Agents - therapeutic use ; Cattle ; Chemistry, Pharmaceutical ; Dental Enamel - metabolism ; Dental Enamel - pathology ; Dental Pellicle - pathology ; Dentin - metabolism ; Dentin - pathology ; Dentistry ; Fluorides - pharmacokinetics ; Fluorides - therapeutic use ; Silicon Dioxide - therapeutic use ; Tooth Abrasion - classification ; Tooth Demineralization - prevention & control ; Tooth Discoloration - therapy ; Tooth Remineralization ; Toothbrushing - instrumentation ; Toothpastes - therapeutic use ; Treatment Outcome ; Triclosan - therapeutic use</subject><ispartof>International dental journal, 2005, Vol.55 (3 Suppl 1), p.197-202</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16004254$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Pickles, M J</creatorcontrib><creatorcontrib>Evans, M</creatorcontrib><creatorcontrib>Philpotts, C J</creatorcontrib><creatorcontrib>Joiner, A</creatorcontrib><creatorcontrib>Lynch, R J M</creatorcontrib><creatorcontrib>Noel, N</creatorcontrib><creatorcontrib>Laucello, M</creatorcontrib><title>In vitro efficacy of a whitening toothpaste containing calcium carbonate and perlite</title><title>International dental journal</title><addtitle>Int Dent J</addtitle><description>The studies described in this paper aimed to assess the stain removal efficacy, fluoride efficacy and abrasivity to enamel and dentine of a new whitening toothpaste containing calcium carbonate and perlite, using appropriate in vitro models.
Stain removal efficacy was assessed using the pellicle cleaning ratio (PCR) method. Fluoride efficacy was assessed using remineralisation, demineralisation and fluoride-uptake methods. Abrasivity was assessed using an enamel and dentine wear method.
The results showed that the new whitening toothpaste was able to remove extrinsic tooth stain more effectively than three commercially available toothpaste formulations. The fluoride efficacy was superior to a non-fluoridated control and was not significantly different to a clinically tested fluoride-containing toothpaste. The abrasivity data showed that the calcium carbonate/perlite toothpaste is no more abrasive to enamel or dentine than two other commercially available whitening toothpastes.
The studies show that the new whitening toothpaste is effective in extrinsic stain removal, has an efficacious fluoride source and does not have an undue degree of abrasivity to enamel or dentine compared to other relevant commercially available products.</description><subject>Aluminum Oxide - therapeutic use</subject><subject>Animals</subject><subject>Anti-Infective Agents, Local - therapeutic use</subject><subject>Calcium Carbonate - therapeutic use</subject><subject>Cariostatic Agents - pharmacokinetics</subject><subject>Cariostatic Agents - therapeutic use</subject><subject>Cattle</subject><subject>Chemistry, Pharmaceutical</subject><subject>Dental Enamel - metabolism</subject><subject>Dental Enamel - pathology</subject><subject>Dental Pellicle - pathology</subject><subject>Dentin - metabolism</subject><subject>Dentin - pathology</subject><subject>Dentistry</subject><subject>Fluorides - pharmacokinetics</subject><subject>Fluorides - therapeutic use</subject><subject>Silicon Dioxide - therapeutic use</subject><subject>Tooth Abrasion - classification</subject><subject>Tooth Demineralization - prevention & control</subject><subject>Tooth Discoloration - therapy</subject><subject>Tooth Remineralization</subject><subject>Toothbrushing - instrumentation</subject><subject>Toothpastes - therapeutic use</subject><subject>Treatment Outcome</subject><subject>Triclosan - therapeutic use</subject><issn>0020-6539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kDFPwzAQhT2AaCn8BWQxsCWcHds4I6qgVKrEUubIdhzqKrFD4kD77zFQbnl39753wyF0SyAnqe73OZEPPOMlP-QUgOdRA4CA_HCG5gAUMsGLcoYux3EPwGQB4gLNiEg95WyOtmuPP10cArZN44wyRxwarPDXzkXrnX_HMYS469UYLTbBR-V-t0a1xk1d0kEHr5KpfI17O7Qpd4XOG9WO9vqkC_T2_LRdvmSb19V6-bjJekJZzChTxmrOLRSSGGqgIMYYoWsBhNE0sIYJ0JJbCY0oiK25LHXNkskkT8QC3f3d7YfwMdkxVp0bjW1b5W2YxkpIIBTKH_DmBE66s3XVD65Tw7H6_0PxDTPHYFw</recordid><startdate>2005</startdate><enddate>2005</enddate><creator>Pickles, M J</creator><creator>Evans, M</creator><creator>Philpotts, C J</creator><creator>Joiner, A</creator><creator>Lynch, R J M</creator><creator>Noel, N</creator><creator>Laucello, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2005</creationdate><title>In vitro efficacy of a whitening toothpaste containing calcium carbonate and perlite</title><author>Pickles, M J ; Evans, M ; Philpotts, C J ; Joiner, A ; Lynch, R J M ; Noel, N ; Laucello, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p124t-24aceb55e0381c2c031ccc6bd6014231c4f460b85e80f631ed589bd4142485423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aluminum Oxide - therapeutic use</topic><topic>Animals</topic><topic>Anti-Infective Agents, Local - therapeutic use</topic><topic>Calcium Carbonate - therapeutic use</topic><topic>Cariostatic Agents - pharmacokinetics</topic><topic>Cariostatic Agents - therapeutic use</topic><topic>Cattle</topic><topic>Chemistry, Pharmaceutical</topic><topic>Dental Enamel - metabolism</topic><topic>Dental Enamel - pathology</topic><topic>Dental Pellicle - pathology</topic><topic>Dentin - metabolism</topic><topic>Dentin - pathology</topic><topic>Dentistry</topic><topic>Fluorides - pharmacokinetics</topic><topic>Fluorides - therapeutic use</topic><topic>Silicon Dioxide - therapeutic use</topic><topic>Tooth Abrasion - classification</topic><topic>Tooth Demineralization - prevention & control</topic><topic>Tooth Discoloration - therapy</topic><topic>Tooth Remineralization</topic><topic>Toothbrushing - instrumentation</topic><topic>Toothpastes - therapeutic use</topic><topic>Treatment Outcome</topic><topic>Triclosan - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Pickles, M J</creatorcontrib><creatorcontrib>Evans, M</creatorcontrib><creatorcontrib>Philpotts, C J</creatorcontrib><creatorcontrib>Joiner, A</creatorcontrib><creatorcontrib>Lynch, R J M</creatorcontrib><creatorcontrib>Noel, N</creatorcontrib><creatorcontrib>Laucello, M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>International dental journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Pickles, M J</au><au>Evans, M</au><au>Philpotts, C J</au><au>Joiner, A</au><au>Lynch, R J M</au><au>Noel, N</au><au>Laucello, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In vitro efficacy of a whitening toothpaste containing calcium carbonate and perlite</atitle><jtitle>International dental journal</jtitle><addtitle>Int Dent J</addtitle><date>2005</date><risdate>2005</risdate><volume>55</volume><issue>3 Suppl 1</issue><spage>197</spage><epage>202</epage><pages>197-202</pages><issn>0020-6539</issn><abstract>The studies described in this paper aimed to assess the stain removal efficacy, fluoride efficacy and abrasivity to enamel and dentine of a new whitening toothpaste containing calcium carbonate and perlite, using appropriate in vitro models.
Stain removal efficacy was assessed using the pellicle cleaning ratio (PCR) method. Fluoride efficacy was assessed using remineralisation, demineralisation and fluoride-uptake methods. Abrasivity was assessed using an enamel and dentine wear method.
The results showed that the new whitening toothpaste was able to remove extrinsic tooth stain more effectively than three commercially available toothpaste formulations. The fluoride efficacy was superior to a non-fluoridated control and was not significantly different to a clinically tested fluoride-containing toothpaste. The abrasivity data showed that the calcium carbonate/perlite toothpaste is no more abrasive to enamel or dentine than two other commercially available whitening toothpastes.
The studies show that the new whitening toothpaste is effective in extrinsic stain removal, has an efficacious fluoride source and does not have an undue degree of abrasivity to enamel or dentine compared to other relevant commercially available products.</abstract><cop>England</cop><pmid>16004254</pmid><doi>10.1111/j.1875-595x.2005.tb00060.x</doi><tpages>6</tpages></addata></record> |
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| ispartof | International dental journal, 2005, Vol.55 (3 Suppl 1), p.197-202 |
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| source | Wiley Online Library Journals【Remote access available】; MEDLINE; Free E-Journal (出版社公開部分のみ）; Alma/SFX Local Collection |
| subjects | Aluminum Oxide - therapeutic use Animals Anti-Infective Agents, Local - therapeutic use Calcium Carbonate - therapeutic use Cariostatic Agents - pharmacokinetics Cariostatic Agents - therapeutic use Cattle Chemistry, Pharmaceutical Dental Enamel - metabolism Dental Enamel - pathology Dental Pellicle - pathology Dentin - metabolism Dentin - pathology Dentistry Fluorides - pharmacokinetics Fluorides - therapeutic use Silicon Dioxide - therapeutic use Tooth Abrasion - classification Tooth Demineralization - prevention & control Tooth Discoloration - therapy Tooth Remineralization Toothbrushing - instrumentation Toothpastes - therapeutic use Treatment Outcome Triclosan - therapeutic use |
| title | In vitro efficacy of a whitening toothpaste containing calcium carbonate and perlite |
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