3alpha,5alpha-THP: a potential plasma neurosteroid biomarker in Alzheimer's disease and perhaps non-Alzheimer's dementia

A plasma biomarker for neurodegenerative disease is desirable because blood is relatively simple to obtain compared with other biological samples such as cerebrospinal fluid. Recent literature suggests that neurosteroid metabolism may be altered in Alzheimer's disease (AD). We sought to measure...

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Veröffentlicht in:	Psychopharmacology 2006-06, Vol.186 (3), p.481-485
Hauptverfasser:	Smith, Charles D, Wekstein, David R, Markesbery, William R, Frye, Cheryl A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Alzheimer Disease - blood Biomarkers - blood Case-Control Studies Dementia - blood Estradiol - blood Female Humans Male Pregnanolone - blood Progesterone - blood Testosterone Congeners - blood
Online-Zugang:	Volltext
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