Multimodality expression profiling shows SEPT9 to be overexpressed in a wide range of human tumours

Septins are an evolutionarily conserved family of GTPases with diverse functions including roles in cytokinesis that have been implicated in neoplasia. To address the potential role of SEPT9 in tumorigenesis, we assessed the expression of SEPT9 in 7287 fresh frozen human tissue samples and 292 human...

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Veröffentlicht in:	Oncogene 2005-07, Vol.24 (29), p.4688-4700
Hauptverfasser:	Scott, Michael, Hyland, Paula L, McGregor, Gordon, Hillan, Kenneth J, Russell, S E Hilary, Hall, Peter A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antisera Apoptosis Biological and medical sciences Biology Breast Breast cancer Cell Biology Cell lines Cell Movement Cell physiology Cell Proliferation Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Cytokinesis Endometrium Esophagus Fundamental and applied biological sciences. Psychology Gene Expression Profiling Gene Expression Regulation, Neoplastic GTP Phosphohydrolases - genetics Human Genetics Humans Immunohistochemistry Internal Medicine Isoforms Medicine Medicine & Public Health Molecular and cellular biology mRNA Neoplasms - genetics Neoplasms - physiopathology Oligonucleotide Array Sequence Analysis Oncology original-paper Ovarian cancer Paraffin Proteins Reverse Transcriptase Polymerase Chain Reaction Septins Thyroid Tumorigenesis Tumors
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