Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae)
The sporontocidal activity of three steroids (SN‐1, SN‐2 and SN‐4) from Solanum nudum Dunal (Solanaceae) was determined against naturally circulating isolates of Plasmodium vivax in Anopheles albimanus. Laboratory‐reared Anopheles albimanus mosquitoes were infected with P. vivax from gametocytemic b...
Gespeichert in:
| Veröffentlicht in: | Phytotherapy research 2006-06, Vol.20 (6), p.444-447 |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 447 |
|---|---|
| container_issue | 6 |
| container_start_page | 444 |
| container_title | Phytotherapy research |
| container_volume | 20 |
| creator | Arango, Eliana Londoño, Berlin Segura, Cesar Solarte, Yezid Herrera, Socrates Saez, Jairo Carmona-Fonseca, Jaime Blair, Silvia |
| description | The sporontocidal activity of three steroids (SN‐1, SN‐2 and SN‐4) from Solanum nudum Dunal (Solanaceae) was determined against naturally circulating isolates of Plasmodium vivax in Anopheles albimanus. Laboratory‐reared Anopheles albimanus mosquitoes were infected with P. vivax from gametocytemic blood of volunteers resident in Buenaventura, Valle del Cauca (Colombian Pacific Coast) by using an artificial membrane feeder. Prior to mosquito feeding, gametocytemic blood was centrifuged, plasma was separated, packed blood red cells were washed with RPMI 1640 and then resuspended in non‐immune AB serum, then the steroids were added at different doses. On day 7 after infection, the presence and number of oocysts in mosquitoes was determined. The steroid SN‐2 reduced the infection of mosquitoes by 90% and the mean number of oocysts by 60%. These data confirmed that the experimental steroid is capable of interrupting the sporogonic development of P. vivax in Anopheles albimanus. This experimental steroid has potential for transmission blocking in vivax malaria. Copyright © 2006 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/ptr.1874 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68008931</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68008931</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3874-4e77d31f0bc3974ed203ed60713c5911e5f8e71fcade9f85e8ca399e4f3f76223</originalsourceid><addsrcrecordid>eNp10EFvFCEUB3BibOy2mvgJDBdNPUyFYWYYjrXWbc1WN1qjN8IyD8UyMMLO2v32st2JPXmB8PKDx_sj9JySU0pI-WZYx1Pa8uoRmlEiREFrzh6jGRE1LSrafj9ERyn9IoSIklRP0CFtGipYzWcoLiNswK9t8DgYnIYQw4_gt7vD0qnUh86OPd7YjbrD1uMzH4af4CBh5Va2V35MeLXFaQ0x2C7trn0JLpd77Mcur-9Grxw-uS8qDQpeP0UHRrkEz6b9GH19f3FzflksPs2vzs8WhWZ5lKICzjtGDVlpJngFXUkYdA3hlOlaUAq1aYFTo1UHwrQ1tFoxIaAyzPCmLNkxerV_d4jh9whpLXubNLj8EQhjkk1LSCsYzfBkD3UMKUUwcoh5tLiVlMhdvjLnK3f5ZvpienNc9dA9wCnQDF5OQCWtnInKa5seHG_LrER2xd79sQ62_20olzefp8aTtznqu39exVvZcMZr-e3jXL6dL6hYXl_LD-wvfF2h_Q</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68008931</pqid></control><display><type>article</type><title>Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae)</title><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Arango, Eliana ; Londoño, Berlin ; Segura, Cesar ; Solarte, Yezid ; Herrera, Socrates ; Saez, Jairo ; Carmona-Fonseca, Jaime ; Blair, Silvia</creator><creatorcontrib>Arango, Eliana ; Londoño, Berlin ; Segura, Cesar ; Solarte, Yezid ; Herrera, Socrates ; Saez, Jairo ; Carmona-Fonseca, Jaime ; Blair, Silvia</creatorcontrib><description>The sporontocidal activity of three steroids (SN‐1, SN‐2 and SN‐4) from Solanum nudum Dunal (Solanaceae) was determined against naturally circulating isolates of Plasmodium vivax in Anopheles albimanus. Laboratory‐reared Anopheles albimanus mosquitoes were infected with P. vivax from gametocytemic blood of volunteers resident in Buenaventura, Valle del Cauca (Colombian Pacific Coast) by using an artificial membrane feeder. Prior to mosquito feeding, gametocytemic blood was centrifuged, plasma was separated, packed blood red cells were washed with RPMI 1640 and then resuspended in non‐immune AB serum, then the steroids were added at different doses. On day 7 after infection, the presence and number of oocysts in mosquitoes was determined. The steroid SN‐2 reduced the infection of mosquitoes by 90% and the mean number of oocysts by 60%. These data confirmed that the experimental steroid is capable of interrupting the sporogonic development of P. vivax in Anopheles albimanus. This experimental steroid has potential for transmission blocking in vivax malaria. Copyright © 2006 John Wiley & Sons, Ltd.</description><identifier>ISSN: 0951-418X</identifier><identifier>EISSN: 1099-1573</identifier><identifier>DOI: 10.1002/ptr.1874</identifier><identifier>PMID: 16619357</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>An. albimanus ; Animals ; Anopheles - parasitology ; Biological and medical sciences ; Disease Transmission, Infectious - prevention & control ; General pharmacology ; Malaria, Vivax - prevention & control ; Medical sciences ; P. vivax ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Plant Extracts - pharmacology ; Plasmodium vivax - drug effects ; S. nudum ; Solanum - chemistry ; Spores, Protozoan - drug effects ; sporogony ; steroids ; Steroids - isolation & purification ; Steroids - pharmacology ; transmission blocking</subject><ispartof>Phytotherapy research, 2006-06, Vol.20 (6), p.444-447</ispartof><rights>Copyright © 2006 John Wiley & Sons, Ltd.</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3874-4e77d31f0bc3974ed203ed60713c5911e5f8e71fcade9f85e8ca399e4f3f76223</citedby><cites>FETCH-LOGICAL-c3874-4e77d31f0bc3974ed203ed60713c5911e5f8e71fcade9f85e8ca399e4f3f76223</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fptr.1874$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fptr.1874$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17825739$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16619357$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Arango, Eliana</creatorcontrib><creatorcontrib>Londoño, Berlin</creatorcontrib><creatorcontrib>Segura, Cesar</creatorcontrib><creatorcontrib>Solarte, Yezid</creatorcontrib><creatorcontrib>Herrera, Socrates</creatorcontrib><creatorcontrib>Saez, Jairo</creatorcontrib><creatorcontrib>Carmona-Fonseca, Jaime</creatorcontrib><creatorcontrib>Blair, Silvia</creatorcontrib><title>Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae)</title><title>Phytotherapy research</title><addtitle>Phytother. Res</addtitle><description>The sporontocidal activity of three steroids (SN‐1, SN‐2 and SN‐4) from Solanum nudum Dunal (Solanaceae) was determined against naturally circulating isolates of Plasmodium vivax in Anopheles albimanus. Laboratory‐reared Anopheles albimanus mosquitoes were infected with P. vivax from gametocytemic blood of volunteers resident in Buenaventura, Valle del Cauca (Colombian Pacific Coast) by using an artificial membrane feeder. Prior to mosquito feeding, gametocytemic blood was centrifuged, plasma was separated, packed blood red cells were washed with RPMI 1640 and then resuspended in non‐immune AB serum, then the steroids were added at different doses. On day 7 after infection, the presence and number of oocysts in mosquitoes was determined. The steroid SN‐2 reduced the infection of mosquitoes by 90% and the mean number of oocysts by 60%. These data confirmed that the experimental steroid is capable of interrupting the sporogonic development of P. vivax in Anopheles albimanus. This experimental steroid has potential for transmission blocking in vivax malaria. Copyright © 2006 John Wiley & Sons, Ltd.</description><subject>An. albimanus</subject><subject>Animals</subject><subject>Anopheles - parasitology</subject><subject>Biological and medical sciences</subject><subject>Disease Transmission, Infectious - prevention & control</subject><subject>General pharmacology</subject><subject>Malaria, Vivax - prevention & control</subject><subject>Medical sciences</subject><subject>P. vivax</subject><subject>Pharmacognosy. Homeopathy. Health food</subject><subject>Pharmacology. Drug treatments</subject><subject>Plant Extracts - pharmacology</subject><subject>Plasmodium vivax - drug effects</subject><subject>S. nudum</subject><subject>Solanum - chemistry</subject><subject>Spores, Protozoan - drug effects</subject><subject>sporogony</subject><subject>steroids</subject><subject>Steroids - isolation & purification</subject><subject>Steroids - pharmacology</subject><subject>transmission blocking</subject><issn>0951-418X</issn><issn>1099-1573</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10EFvFCEUB3BibOy2mvgJDBdNPUyFYWYYjrXWbc1WN1qjN8IyD8UyMMLO2v32st2JPXmB8PKDx_sj9JySU0pI-WZYx1Pa8uoRmlEiREFrzh6jGRE1LSrafj9ERyn9IoSIklRP0CFtGipYzWcoLiNswK9t8DgYnIYQw4_gt7vD0qnUh86OPd7YjbrD1uMzH4af4CBh5Va2V35MeLXFaQ0x2C7trn0JLpd77Mcur-9Grxw-uS8qDQpeP0UHRrkEz6b9GH19f3FzflksPs2vzs8WhWZ5lKICzjtGDVlpJngFXUkYdA3hlOlaUAq1aYFTo1UHwrQ1tFoxIaAyzPCmLNkxerV_d4jh9whpLXubNLj8EQhjkk1LSCsYzfBkD3UMKUUwcoh5tLiVlMhdvjLnK3f5ZvpienNc9dA9wCnQDF5OQCWtnInKa5seHG_LrER2xd79sQ62_20olzefp8aTtznqu39exVvZcMZr-e3jXL6dL6hYXl_LD-wvfF2h_Q</recordid><startdate>200606</startdate><enddate>200606</enddate><creator>Arango, Eliana</creator><creator>Londoño, Berlin</creator><creator>Segura, Cesar</creator><creator>Solarte, Yezid</creator><creator>Herrera, Socrates</creator><creator>Saez, Jairo</creator><creator>Carmona-Fonseca, Jaime</creator><creator>Blair, Silvia</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200606</creationdate><title>Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae)</title><author>Arango, Eliana ; Londoño, Berlin ; Segura, Cesar ; Solarte, Yezid ; Herrera, Socrates ; Saez, Jairo ; Carmona-Fonseca, Jaime ; Blair, Silvia</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3874-4e77d31f0bc3974ed203ed60713c5911e5f8e71fcade9f85e8ca399e4f3f76223</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>An. albimanus</topic><topic>Animals</topic><topic>Anopheles - parasitology</topic><topic>Biological and medical sciences</topic><topic>Disease Transmission, Infectious - prevention & control</topic><topic>General pharmacology</topic><topic>Malaria, Vivax - prevention & control</topic><topic>Medical sciences</topic><topic>P. vivax</topic><topic>Pharmacognosy. Homeopathy. Health food</topic><topic>Pharmacology. Drug treatments</topic><topic>Plant Extracts - pharmacology</topic><topic>Plasmodium vivax - drug effects</topic><topic>S. nudum</topic><topic>Solanum - chemistry</topic><topic>Spores, Protozoan - drug effects</topic><topic>sporogony</topic><topic>steroids</topic><topic>Steroids - isolation & purification</topic><topic>Steroids - pharmacology</topic><topic>transmission blocking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Arango, Eliana</creatorcontrib><creatorcontrib>Londoño, Berlin</creatorcontrib><creatorcontrib>Segura, Cesar</creatorcontrib><creatorcontrib>Solarte, Yezid</creatorcontrib><creatorcontrib>Herrera, Socrates</creatorcontrib><creatorcontrib>Saez, Jairo</creatorcontrib><creatorcontrib>Carmona-Fonseca, Jaime</creatorcontrib><creatorcontrib>Blair, Silvia</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Phytotherapy research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Arango, Eliana</au><au>Londoño, Berlin</au><au>Segura, Cesar</au><au>Solarte, Yezid</au><au>Herrera, Socrates</au><au>Saez, Jairo</au><au>Carmona-Fonseca, Jaime</au><au>Blair, Silvia</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae)</atitle><jtitle>Phytotherapy research</jtitle><addtitle>Phytother. Res</addtitle><date>2006-06</date><risdate>2006</risdate><volume>20</volume><issue>6</issue><spage>444</spage><epage>447</epage><pages>444-447</pages><issn>0951-418X</issn><eissn>1099-1573</eissn><abstract>The sporontocidal activity of three steroids (SN‐1, SN‐2 and SN‐4) from Solanum nudum Dunal (Solanaceae) was determined against naturally circulating isolates of Plasmodium vivax in Anopheles albimanus. Laboratory‐reared Anopheles albimanus mosquitoes were infected with P. vivax from gametocytemic blood of volunteers resident in Buenaventura, Valle del Cauca (Colombian Pacific Coast) by using an artificial membrane feeder. Prior to mosquito feeding, gametocytemic blood was centrifuged, plasma was separated, packed blood red cells were washed with RPMI 1640 and then resuspended in non‐immune AB serum, then the steroids were added at different doses. On day 7 after infection, the presence and number of oocysts in mosquitoes was determined. The steroid SN‐2 reduced the infection of mosquitoes by 90% and the mean number of oocysts by 60%. These data confirmed that the experimental steroid is capable of interrupting the sporogonic development of P. vivax in Anopheles albimanus. This experimental steroid has potential for transmission blocking in vivax malaria. Copyright © 2006 John Wiley & Sons, Ltd.</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>16619357</pmid><doi>10.1002/ptr.1874</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0951-418X |
| ispartof | Phytotherapy research, 2006-06, Vol.20 (6), p.444-447 |
| issn | 0951-418X 1099-1573 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68008931 |
| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | An. albimanus Animals Anopheles - parasitology Biological and medical sciences Disease Transmission, Infectious - prevention & control General pharmacology Malaria, Vivax - prevention & control Medical sciences P. vivax Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - pharmacology Plasmodium vivax - drug effects S. nudum Solanum - chemistry Spores, Protozoan - drug effects sporogony steroids Steroids - isolation & purification Steroids - pharmacology transmission blocking |
| title | Prevention of sporogony of Plasmodium vivax in Anopheles albimanus by steroids of Solanum nudum Dunal (Solanaceae) |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-21T01%3A21%3A07IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevention%20of%20sporogony%20of%20Plasmodium%20vivax%20in%20Anopheles%20albimanus%20by%20steroids%20of%20Solanum%20nudum%20Dunal%20(Solanaceae)&rft.jtitle=Phytotherapy%20research&rft.au=Arango,%20Eliana&rft.date=2006-06&rft.volume=20&rft.issue=6&rft.spage=444&rft.epage=447&rft.pages=444-447&rft.issn=0951-418X&rft.eissn=1099-1573&rft_id=info:doi/10.1002/ptr.1874&rft_dat=%3Cproquest_cross%3E68008931%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68008931&rft_id=info:pmid/16619357&rfr_iscdi=true |