Proteins differentially expressed in response to nicotine in five rat brain regions: Identification using a 2-DE/MS-based proteomics approach

To determine protein expression patterns within the central nervous system (CNS) in response to nicotine, 2‐DE/MS was performed on samples from five brain regions of rats that had received nicotine bitartrate by osmotic minipump infusion at a dose of 3.15 mg/kg/day for 7 days. After spot matching an...

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Veröffentlicht in:	Proteomics (Weinheim) 2006-05, Vol.6 (10), p.3138-3153
Hauptverfasser:	Hwang, Yoon Y., Li, Ming D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Addiction Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Brain - anatomy & histology Brain - drug effects Brain - metabolism Brain regions Dynamins - biosynthesis Electrophoresis, Gel, Two-Dimensional Fructose-Bisphosphate Aldolase - biosynthesis Fundamental and applied biological sciences. Psychology Glycolysis HSC70 Heat-Shock Proteins - biosynthesis Male Miscellaneous Nicotine Nicotine - pharmacology Nicotinic Agonists - pharmacology Phosphopyruvate Hydratase - biosynthesis Proteins Proteome Proteome - biosynthesis Rat Rats Rats, Sprague-Dawley Receptors, Laminin - biosynthesis Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
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