Haplotype-based association analysis of 56 functional candidate genes in the IBD6 locus on chromosome 19

Evidence from four independent linkage studies and two meta-analyses of genome-wide data support the existence of a locus conferring susceptibility to inflammatory bowel diseases (IBD) in chromosomal region 19p. Identification of a susceptibility allele in this ∼28.5 Mb region with over 600 genes is...

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Veröffentlicht in:	European journal of human genetics : EJHG 2006-06, Vol.14 (6), p.780-790
Hauptverfasser:	Tello-Ruiz, Marcela Karey, Curley, Christine, DelMonte, Terrye, Giallourakis, Cosmas, Kirby, Andrew, Miller, Kathryn, Wild, Gary, Cohen, Albert, Langelier, Diane, Latiano, Anna, Wedemeyer, Neils, Lander, Eric, Schreiber, Stefan, Annese, Vito, Daly, Mark J, Rioux, John D
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Association analysis Bioinformatics Biological and medical sciences Biomedical and Life Sciences Biomedicine Celiac disease Celiac Disease - genetics Chromosome 19 Chromosomes Chromosomes, Human, Pair 19 - genetics Cohort Studies Crohn's disease Cytogenetics Data processing Female Gastroenterology Gene Expression General aspects. Genetic counseling Genetics Genomes Haplotypes Haplotypes - genetics Human Genetics Humans Inflammatory bowel disease Inflammatory bowel diseases Inflammatory Bowel Diseases - genetics Intercellular adhesion molecule 1 Interleukin 1 Intestine Male Medical genetics Medical sciences Meta-Analysis as Topic Polymorphism, Single Nucleotide Quantitative Trait Loci - genetics Single-nucleotide polymorphism Studies
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