Macrophage Migration Inhibitory Factor Contributes to Host Defense against Acute Trypanosoma cruzi Infection

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine that is involved in the host defense against several pathogens. Here we used MIF⁻/⁻ mice to determine the role of endogenous MIF in the regulation of the host immune response against Trypanosoma cruzi infection. MIF⁻/⁻ mice d...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Infection and Immunity 2006-06, Vol.74 (6), p.3170-3179
Hauptverfasser:	Reyes, José L, Terrazas, Luis I, Espinoza, Bertha, Cruz-Robles, David, Soto, Virgilia, Rivera-Montoya, Irma, Gómez-García, Lorena, Snider, Heidi, Satoskar, Abhay R, Rodríguez-Sosa, Miriam
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Antibodies, Protozoan - blood Biological and medical sciences blood Chagas Disease - immunology Chagas Disease - pathology Fundamental and applied biological sciences. Psychology heart Host Response and Inflammation Human protozoal diseases immune response Immunoglobulin G - blood immunoglobulins immunopathology Infectious diseases interferon-gamma Interferon-gamma - biosynthesis Interleukin-1 - biosynthesis interleukin-10 interleukin-12 Interleukin-12 - biosynthesis interleukin-18 interleukin-1beta interleukin-4 macrophage migration inhibitory factors Macrophage Migration-Inhibitory Factors - physiology Male Medical sciences Mice Mice, Inbred BALB C Microbiology Muscle, Skeletal - pathology Myocardium - pathology nitric oxide synthase Nitric Oxide Synthase Type II - genetics parasitemia Parasitemia - immunology Parasitic diseases pathogens Protozoal diseases RNA, Messenger - analysis skeletal muscle splenocytes Trypanosoma cruzi Trypanosoma cruzi - immunology Trypanosomiasis tumor necrosis factor-alpha Tumor Necrosis Factor-alpha - biosynthesis
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!