Effects of 9-cis-Retinoic Acid on the Insulin-Like Growth Factor Axis in Former Smokers

Insulin-like growth factor (IGF) axis has been associated with the risk of lung cancer. 9-cis-retinoic acid (9-cis-RA) has shown potential chemopreventive activities in former smokers. This study was designed to evaluate the effects of 9-cis-RA on IGF axis in former smokers to identify any benefit t...

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Veröffentlicht in:	Journal of clinical oncology 2005-07, Vol.23 (19), p.4439-4449
Hauptverfasser:	LEE, Ho-Young, YOON SOO CHANG, HAN, Ji-Youn, LIU, Diane D, LEE, J. Jack, LOTAN, Reuben, SPITZ, Margaret R, WAUN KI HONG
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Biomarkers Female Humans Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor I - metabolism Male Medical sciences Middle Aged Placebos Radioimmunoassay Receptors, Retinoic Acid - metabolism Smoking - adverse effects Tretinoin - pharmacology Tumors
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