Investigation on the role of cell transcriptional factor Sp1 and HIV-1 TAT protein in PML onset or development

JC virus (JCV) causes progressive multifocal leukoencephalopathy (PML), characterized by multiple areas of demyelination and attendant loss of brain function. PML is often associated with immunodepression and it is significantly frequent in AIDS patients. The viral genome is divided into early and l...

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Veröffentlicht in:	Journal of cellular physiology 2005-09, Vol.204 (3), p.913-918
Hauptverfasser:	Mischitelli, M., Fioriti, D., Videtta, M., Degener, A.M., Antinori, A., Cinque, P., Giordano, A., Pietropaolo, V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Base Sequence Binding Sites Consensus Sequence - genetics Disease Progression Gene Products, tat - metabolism HIV Seronegativity HIV Seropositivity - cerebrospinal fluid HIV Seropositivity - complications HIV Seropositivity - metabolism HIV Seropositivity - virology Humans JC Virus - genetics JC Virus - isolation & purification Leukoencephalopathy, Progressive Multifocal - complications Leukoencephalopathy, Progressive Multifocal - metabolism Leukoencephalopathy, Progressive Multifocal - pathology Leukoencephalopathy, Progressive Multifocal - virology Middle Aged Molecular Sequence Data Sequence Alignment Sp1 Transcription Factor - metabolism tat Gene Products, Human Immunodeficiency Virus
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