p38 mitogen-activated protein kinase contributes to cell cycle regulation by cAMP in FRTL-5 thyroid cells

Objective: Thyrotropin activates the cAMP pathway in thyroid cells, and stimulates cell cycle progression in cooperation with insulin or insulin-like growth factor-I. Because p38 mitogen-activated protein kinases (p38 MAPKs) were stimulated by cAMP in the FRTL-5 rat thyroid cell line, we investigate...

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Veröffentlicht in:	European journal of endocrinology 2005-07, Vol.153 (1), p.123-133
Hauptverfasser:	Corrèze, C, Blondeau, J-P, Pomérance, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences CDC2-CDC28 Kinases - metabolism Cells, Cultured Colforsin - pharmacology Cyclic AMP - metabolism Cyclin-Dependent Kinase 2 Endocrinopathies Enzyme Inhibitors - pharmacology Experimental Studies Fundamental and applied biological sciences. Psychology G1 Phase - physiology Hypoglycemic Agents - pharmacology Imidazoles - pharmacology Insulin - pharmacology Medical sciences p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors p38 Mitogen-Activated Protein Kinases - metabolism Phosphorylation - drug effects Pyridines - pharmacology Rats S Phase - physiology Signal Transduction - physiology Threonine - metabolism Thyroid Gland - cytology Thyroid Gland - enzymology Tyrosine - metabolism Vertebrates: endocrinology
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