The road much traveled: trafficking in the cell nucleus
Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nu...
Gespeichert in:
Veröffentlicht in: | Current opinion in cell biology 2006-06, Vol.18 (3), p.284-290 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 290 |
---|---|
container_issue | 3 |
container_start_page | 284 |
container_title | Current opinion in cell biology |
container_volume | 18 |
creator | Gorski, Stanislaw A Dundr, Miroslav Misteli, Tom |
description | Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function. |
doi_str_mv | 10.1016/j.ceb.2006.03.002 |
format | Article |
fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67994636</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0955067406000457</els_id><sourcerecordid>20370927</sourcerecordid><originalsourceid>FETCH-LOGICAL-c448t-af5a393ff9c1c013df3e62f2940c1c337e2ba5b1c843daf4672e9fc00f2f3aae3</originalsourceid><addsrcrecordid>eNqFkE1LAzEQhoMotlZ_gBfZk7ddJx_NNnqS4hcUvNRzyGYnNnW7q8luwX9vSgve9DTD8Lwvw0PIJYWCApU368JiVTAAWQAvANgRGdNZqXIQFI7JGNR0moMsxYicxbiGBAJTp2REpWRUqNmYlMsVZqEzdbYZ7Crrg9lig_XtbnPO2w_fvme-zfqEWWyarB1sg0M8JyfONBEvDnNC3h4flvPnfPH69DK_X-RWiFmfGzc1XHHnlKUWKK8dR8kcUwLSgfMSWWWmFbUzwWvjhCwZKmcBHHPcGOQTcr3v_Qzd14Cx1xsfd4-YFrshalkqJSSX_4IMeAmKlQmke9CGLsaATn8GvzHhW1PQO616rZNWvdOqgeukNWWuDuVDtcH6N3HwmIC7PYDJxdZj0NF6bC3WPqDtdd35P-p_AChVhyI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>20370927</pqid></control><display><type>article</type><title>The road much traveled: trafficking in the cell nucleus</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Gorski, Stanislaw A ; Dundr, Miroslav ; Misteli, Tom</creator><creatorcontrib>Gorski, Stanislaw A ; Dundr, Miroslav ; Misteli, Tom</creatorcontrib><description>Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.</description><identifier>ISSN: 0955-0674</identifier><identifier>EISSN: 1879-0410</identifier><identifier>DOI: 10.1016/j.ceb.2006.03.002</identifier><identifier>PMID: 16621498</identifier><language>eng</language><publisher>England: Elsevier Ltd</publisher><subject>Active Transport, Cell Nucleus ; Animals ; Cell Nucleus - metabolism ; Diffusion ; Humans ; Models, Biological ; Protein Transport ; RNA - metabolism ; Signal Transduction</subject><ispartof>Current opinion in cell biology, 2006-06, Vol.18 (3), p.284-290</ispartof><rights>2006 Elsevier Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c448t-af5a393ff9c1c013df3e62f2940c1c337e2ba5b1c843daf4672e9fc00f2f3aae3</citedby><cites>FETCH-LOGICAL-c448t-af5a393ff9c1c013df3e62f2940c1c337e2ba5b1c843daf4672e9fc00f2f3aae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0955067406000457$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16621498$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gorski, Stanislaw A</creatorcontrib><creatorcontrib>Dundr, Miroslav</creatorcontrib><creatorcontrib>Misteli, Tom</creatorcontrib><title>The road much traveled: trafficking in the cell nucleus</title><title>Current opinion in cell biology</title><addtitle>Curr Opin Cell Biol</addtitle><description>Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.</description><subject>Active Transport, Cell Nucleus</subject><subject>Animals</subject><subject>Cell Nucleus - metabolism</subject><subject>Diffusion</subject><subject>Humans</subject><subject>Models, Biological</subject><subject>Protein Transport</subject><subject>RNA - metabolism</subject><subject>Signal Transduction</subject><issn>0955-0674</issn><issn>1879-0410</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1LAzEQhoMotlZ_gBfZk7ddJx_NNnqS4hcUvNRzyGYnNnW7q8luwX9vSgve9DTD8Lwvw0PIJYWCApU368JiVTAAWQAvANgRGdNZqXIQFI7JGNR0moMsxYicxbiGBAJTp2REpWRUqNmYlMsVZqEzdbYZ7Crrg9lig_XtbnPO2w_fvme-zfqEWWyarB1sg0M8JyfONBEvDnNC3h4flvPnfPH69DK_X-RWiFmfGzc1XHHnlKUWKK8dR8kcUwLSgfMSWWWmFbUzwWvjhCwZKmcBHHPcGOQTcr3v_Qzd14Cx1xsfd4-YFrshalkqJSSX_4IMeAmKlQmke9CGLsaATn8GvzHhW1PQO616rZNWvdOqgeukNWWuDuVDtcH6N3HwmIC7PYDJxdZj0NF6bC3WPqDtdd35P-p_AChVhyI</recordid><startdate>20060601</startdate><enddate>20060601</enddate><creator>Gorski, Stanislaw A</creator><creator>Dundr, Miroslav</creator><creator>Misteli, Tom</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TM</scope><scope>7X8</scope></search><sort><creationdate>20060601</creationdate><title>The road much traveled: trafficking in the cell nucleus</title><author>Gorski, Stanislaw A ; Dundr, Miroslav ; Misteli, Tom</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c448t-af5a393ff9c1c013df3e62f2940c1c337e2ba5b1c843daf4672e9fc00f2f3aae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Active Transport, Cell Nucleus</topic><topic>Animals</topic><topic>Cell Nucleus - metabolism</topic><topic>Diffusion</topic><topic>Humans</topic><topic>Models, Biological</topic><topic>Protein Transport</topic><topic>RNA - metabolism</topic><topic>Signal Transduction</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gorski, Stanislaw A</creatorcontrib><creatorcontrib>Dundr, Miroslav</creatorcontrib><creatorcontrib>Misteli, Tom</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Nucleic Acids Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Current opinion in cell biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gorski, Stanislaw A</au><au>Dundr, Miroslav</au><au>Misteli, Tom</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The road much traveled: trafficking in the cell nucleus</atitle><jtitle>Current opinion in cell biology</jtitle><addtitle>Curr Opin Cell Biol</addtitle><date>2006-06-01</date><risdate>2006</risdate><volume>18</volume><issue>3</issue><spage>284</spage><epage>290</epage><pages>284-290</pages><issn>0955-0674</issn><eissn>1879-0410</eissn><abstract>Trafficking of RNA molecules and proteins within the cell nucleus is central to genome function. Recent work has revealed the nature of RNA and protein motion within the nucleus and across the nuclear membrane. These studies have given insight into how molecules find their destinations within the nucleus and have uncovered some of the structural properties of the nuclear microenvironment. Control of RNA and protein trafficking is now emerging as a physiological regulatory mechanism in gene expression and nuclear function.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>16621498</pmid><doi>10.1016/j.ceb.2006.03.002</doi><tpages>7</tpages></addata></record> |
fulltext | fulltext |
identifier | ISSN: 0955-0674 |
ispartof | Current opinion in cell biology, 2006-06, Vol.18 (3), p.284-290 |
issn | 0955-0674 1879-0410 |
language | eng |
recordid | cdi_proquest_miscellaneous_67994636 |
source | MEDLINE; Elsevier ScienceDirect Journals |
subjects | Active Transport, Cell Nucleus Animals Cell Nucleus - metabolism Diffusion Humans Models, Biological Protein Transport RNA - metabolism Signal Transduction |
title | The road much traveled: trafficking in the cell nucleus |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T08%3A35%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20road%20much%20traveled:%20trafficking%20in%20the%20cell%20nucleus&rft.jtitle=Current%20opinion%20in%20cell%20biology&rft.au=Gorski,%20Stanislaw%20A&rft.date=2006-06-01&rft.volume=18&rft.issue=3&rft.spage=284&rft.epage=290&rft.pages=284-290&rft.issn=0955-0674&rft.eissn=1879-0410&rft_id=info:doi/10.1016/j.ceb.2006.03.002&rft_dat=%3Cproquest_cross%3E20370927%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=20370927&rft_id=info:pmid/16621498&rft_els_id=S0955067406000457&rfr_iscdi=true |