A Mapping Study of Caspase-3 Activation Following Acute Spinal Cord Contusion in Rats

Spinal cord injury (SCI) initiates a cascade of biochemical changes that results in necrotic and apoptotic cell death. There is evidence that caspase-3 activation and apoptotic cell death occur within hours after SCI. However, the time course and cellular localization of activated caspase-3 has not...

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Veröffentlicht in:	The journal of histochemistry and cytochemistry 2005-07, Vol.53 (7), p.809-819
Hauptverfasser:	McEwen, Melanie L, Springer, Joe E
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Caspase 3 Caspases - metabolism Enzyme Activation Female Immunohistochemistry Laminectomy Macrophages - enzymology Macrophages - metabolism Nerve Tissue Proteins - metabolism Neurons - enzymology Neurons - metabolism Oligodendroglia - enzymology Oligodendroglia - metabolism Rats Rats, Long-Evans Spinal Cord - enzymology Spinal Cord - metabolism Spinal Cord Injuries - enzymology Spinal Cord Injuries - metabolism Spinal Cord Injuries - surgery
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