Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia
Summary Background and objective: The aim of this study was to determine the duration of onset and regression time of sensory and motor blocks, the quality of anaesthesia and postoperative analgesia by the addition of dexmedetomidine to local anaesthetic solution in intravenous regional anaesthesia...
Gespeichert in:
| Veröffentlicht in: | European journal of anaesthesiology 2005-06, Vol.22 (6), p.447-451 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 451 |
|---|---|
| container_issue | 6 |
| container_start_page | 447 |
| container_title | European journal of anaesthesiology |
| container_volume | 22 |
| creator | Esmaoglu, A. Mizrak, A. Akin, A. Turk, Y. Boyaci, A. |
| description | Summary Background and objective: The aim of this study was to determine the duration of onset and regression time of sensory and motor blocks, the quality of anaesthesia and postoperative analgesia by the addition of dexmedetomidine to local anaesthetic solution in intravenous regional anaesthesia (IVRA). Methods: Forty patients scheduled for elective hand surgery participated in this prospective randomized double-blind study. The IVRA was achieved using 3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the control group or 1 μg kg−1 of dexmedetomidine +3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the dexmedetomidine group. The onset and regression times for sensory and motor blocks were recorded. Qualities of anaesthesia, intraoperative and postoperative analgesic requirements were noted. Results: There was no difference between the groups with respect to sensory and motor blocks onset and regression time. The quality of anaesthesia was better in the dexmedetomidine group than the control group and the difference was statistically significant. Intraoperative and postoperative analgesic requirements were greater in the control group than in the dexmedetomidine group. Conclusions: Addition of dexmedetomidine to local anaesthetic solution in IVRA improved the quality of anaesthesia and decreased analgesic requirements, but had no effect on the sensory and motor blocks onset and regression times. |
| doi_str_mv | 10.1017/S0265021505000761 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_67992122</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cupid>10_1017_S0265021505000761</cupid><sourcerecordid>67992122</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3258-15ca58131d6140f8d3d69c8fea2848980a93daca0b22433b55b5f93d6c50d11f3</originalsourceid><addsrcrecordid>eNplkctOwzAQRS0EoqXwAWxQxIJdwI_YdZYV4iUVsQDWlmM7rYsTFzuh8Pc4ahESrKyZOXdmfAeAUwQvEUTTq2eIGYUYUUghhFOG9sAYEUZzTAq2D8ZDOR_qI3AU4yoxNOkOwQjRskwqPgaPM61tZ32b-TrT5rMx2nS-sdq2Jut85qz2Sg5B7UNm2y7ID9P6PmbBLJJMuky20sRuaaKVx-Cgli6ak907Aa-3Ny_X9_n86e7hejbPFcGU54gqSTkiSDNUwJprolmpeG0k5gUvOZQl0VJJWGFcEFJRWtE6pZiiUCNUkwm42PZdB__ep-misVEZ52Rr0m6CTcsSI4wTeP4HXPk-pK2jwIgxiDErEnS2g_oq_V-sg21k-BI_LiWg2AIb7zoT4pvrNyaIpZGuW4pkKySpTY6Tv5ClKB9Sg4xsZUo2VbB6YX6nIyiGE4p_JyTfaySHtQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>216602264</pqid></control><display><type>article</type><title>Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia</title><source>MEDLINE</source><source>Journals@Ovid Ovid Autoload</source><creator>Esmaoglu, A. ; Mizrak, A. ; Akin, A. ; Turk, Y. ; Boyaci, A.</creator><creatorcontrib>Esmaoglu, A. ; Mizrak, A. ; Akin, A. ; Turk, Y. ; Boyaci, A.</creatorcontrib><description>Summary Background and objective: The aim of this study was to determine the duration of onset and regression time of sensory and motor blocks, the quality of anaesthesia and postoperative analgesia by the addition of dexmedetomidine to local anaesthetic solution in intravenous regional anaesthesia (IVRA). Methods: Forty patients scheduled for elective hand surgery participated in this prospective randomized double-blind study. The IVRA was achieved using 3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the control group or 1 μg kg−1 of dexmedetomidine +3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the dexmedetomidine group. The onset and regression times for sensory and motor blocks were recorded. Qualities of anaesthesia, intraoperative and postoperative analgesic requirements were noted. Results: There was no difference between the groups with respect to sensory and motor blocks onset and regression time. The quality of anaesthesia was better in the dexmedetomidine group than the control group and the difference was statistically significant. Intraoperative and postoperative analgesic requirements were greater in the control group than in the dexmedetomidine group. Conclusions: Addition of dexmedetomidine to local anaesthetic solution in IVRA improved the quality of anaesthesia and decreased analgesic requirements, but had no effect on the sensory and motor blocks onset and regression times.</description><identifier>ISSN: 0265-0215</identifier><identifier>EISSN: 1365-2346</identifier><identifier>DOI: 10.1017/S0265021505000761</identifier><identifier>PMID: 15991508</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Analgesics - administration & dosage ; Analgesics - therapeutic use ; Analgesics, Opioid - therapeutic use ; Anesthesia ; Anesthesia, Conduction ; Anesthesia, Intravenous ; Anesthetics, Local - administration & dosage ; Anesthetics, Local - therapeutic use ; Blood Pressure - drug effects ; Dexmedetomidine - administration & dosage ; Dexmedetomidine - therapeutic use ; Double-Blind Method ; Electrocardiography ; Female ; Fentanyl - therapeutic use ; Hand - surgery ; Hemodynamics - drug effects ; Humans ; Lidocaine - administration & dosage ; Lidocaine - therapeutic use ; Male ; Middle Aged ; Nerve Block ; Original Article ; Pain Measurement ; Pain, Postoperative - drug therapy ; Prospective Studies ; Quality ; Studies ; Surgery</subject><ispartof>European journal of anaesthesiology, 2005-06, Vol.22 (6), p.447-451</ispartof><rights>2005 European Society of Anaesthesiology</rights><rights>Copyright Cambridge University Press Jun 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15991508$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Esmaoglu, A.</creatorcontrib><creatorcontrib>Mizrak, A.</creatorcontrib><creatorcontrib>Akin, A.</creatorcontrib><creatorcontrib>Turk, Y.</creatorcontrib><creatorcontrib>Boyaci, A.</creatorcontrib><title>Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia</title><title>European journal of anaesthesiology</title><addtitle>Eur J Anaesthesiol</addtitle><description>Summary Background and objective: The aim of this study was to determine the duration of onset and regression time of sensory and motor blocks, the quality of anaesthesia and postoperative analgesia by the addition of dexmedetomidine to local anaesthetic solution in intravenous regional anaesthesia (IVRA). Methods: Forty patients scheduled for elective hand surgery participated in this prospective randomized double-blind study. The IVRA was achieved using 3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the control group or 1 μg kg−1 of dexmedetomidine +3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the dexmedetomidine group. The onset and regression times for sensory and motor blocks were recorded. Qualities of anaesthesia, intraoperative and postoperative analgesic requirements were noted. Results: There was no difference between the groups with respect to sensory and motor blocks onset and regression time. The quality of anaesthesia was better in the dexmedetomidine group than the control group and the difference was statistically significant. Intraoperative and postoperative analgesic requirements were greater in the control group than in the dexmedetomidine group. Conclusions: Addition of dexmedetomidine to local anaesthetic solution in IVRA improved the quality of anaesthesia and decreased analgesic requirements, but had no effect on the sensory and motor blocks onset and regression times.</description><subject>Adult</subject><subject>Analgesics - administration & dosage</subject><subject>Analgesics - therapeutic use</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Anesthesia</subject><subject>Anesthesia, Conduction</subject><subject>Anesthesia, Intravenous</subject><subject>Anesthetics, Local - administration & dosage</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>Blood Pressure - drug effects</subject><subject>Dexmedetomidine - administration & dosage</subject><subject>Dexmedetomidine - therapeutic use</subject><subject>Double-Blind Method</subject><subject>Electrocardiography</subject><subject>Female</subject><subject>Fentanyl - therapeutic use</subject><subject>Hand - surgery</subject><subject>Hemodynamics - drug effects</subject><subject>Humans</subject><subject>Lidocaine - administration & dosage</subject><subject>Lidocaine - therapeutic use</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nerve Block</subject><subject>Original Article</subject><subject>Pain Measurement</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Prospective Studies</subject><subject>Quality</subject><subject>Studies</subject><subject>Surgery</subject><issn>0265-0215</issn><issn>1365-2346</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNplkctOwzAQRS0EoqXwAWxQxIJdwI_YdZYV4iUVsQDWlmM7rYsTFzuh8Pc4ahESrKyZOXdmfAeAUwQvEUTTq2eIGYUYUUghhFOG9sAYEUZzTAq2D8ZDOR_qI3AU4yoxNOkOwQjRskwqPgaPM61tZ32b-TrT5rMx2nS-sdq2Jut85qz2Sg5B7UNm2y7ID9P6PmbBLJJMuky20sRuaaKVx-Cgli6ak907Aa-3Ny_X9_n86e7hejbPFcGU54gqSTkiSDNUwJprolmpeG0k5gUvOZQl0VJJWGFcEFJRWtE6pZiiUCNUkwm42PZdB__ep-misVEZ52Rr0m6CTcsSI4wTeP4HXPk-pK2jwIgxiDErEnS2g_oq_V-sg21k-BI_LiWg2AIb7zoT4pvrNyaIpZGuW4pkKySpTY6Tv5ClKB9Sg4xsZUo2VbB6YX6nIyiGE4p_JyTfaySHtQ</recordid><startdate>200506</startdate><enddate>200506</enddate><creator>Esmaoglu, A.</creator><creator>Mizrak, A.</creator><creator>Akin, A.</creator><creator>Turk, Y.</creator><creator>Boyaci, A.</creator><general>Cambridge University Press</general><general>European Society of Anaesthesiology</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200506</creationdate><title>Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia</title><author>Esmaoglu, A. ; Mizrak, A. ; Akin, A. ; Turk, Y. ; Boyaci, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3258-15ca58131d6140f8d3d69c8fea2848980a93daca0b22433b55b5f93d6c50d11f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Analgesics - administration & dosage</topic><topic>Analgesics - therapeutic use</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Anesthesia</topic><topic>Anesthesia, Conduction</topic><topic>Anesthesia, Intravenous</topic><topic>Anesthetics, Local - administration & dosage</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>Blood Pressure - drug effects</topic><topic>Dexmedetomidine - administration & dosage</topic><topic>Dexmedetomidine - therapeutic use</topic><topic>Double-Blind Method</topic><topic>Electrocardiography</topic><topic>Female</topic><topic>Fentanyl - therapeutic use</topic><topic>Hand - surgery</topic><topic>Hemodynamics - drug effects</topic><topic>Humans</topic><topic>Lidocaine - administration & dosage</topic><topic>Lidocaine - therapeutic use</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nerve Block</topic><topic>Original Article</topic><topic>Pain Measurement</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Prospective Studies</topic><topic>Quality</topic><topic>Studies</topic><topic>Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Esmaoglu, A.</creatorcontrib><creatorcontrib>Mizrak, A.</creatorcontrib><creatorcontrib>Akin, A.</creatorcontrib><creatorcontrib>Turk, Y.</creatorcontrib><creatorcontrib>Boyaci, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of anaesthesiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Esmaoglu, A.</au><au>Mizrak, A.</au><au>Akin, A.</au><au>Turk, Y.</au><au>Boyaci, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia</atitle><jtitle>European journal of anaesthesiology</jtitle><addtitle>Eur J Anaesthesiol</addtitle><date>2005-06</date><risdate>2005</risdate><volume>22</volume><issue>6</issue><spage>447</spage><epage>451</epage><pages>447-451</pages><issn>0265-0215</issn><eissn>1365-2346</eissn><abstract>Summary Background and objective: The aim of this study was to determine the duration of onset and regression time of sensory and motor blocks, the quality of anaesthesia and postoperative analgesia by the addition of dexmedetomidine to local anaesthetic solution in intravenous regional anaesthesia (IVRA). Methods: Forty patients scheduled for elective hand surgery participated in this prospective randomized double-blind study. The IVRA was achieved using 3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the control group or 1 μg kg−1 of dexmedetomidine +3 mg kg−1 lidocaine diluted with saline to a total volume of 40 mL in the dexmedetomidine group. The onset and regression times for sensory and motor blocks were recorded. Qualities of anaesthesia, intraoperative and postoperative analgesic requirements were noted. Results: There was no difference between the groups with respect to sensory and motor blocks onset and regression time. The quality of anaesthesia was better in the dexmedetomidine group than the control group and the difference was statistically significant. Intraoperative and postoperative analgesic requirements were greater in the control group than in the dexmedetomidine group. Conclusions: Addition of dexmedetomidine to local anaesthetic solution in IVRA improved the quality of anaesthesia and decreased analgesic requirements, but had no effect on the sensory and motor blocks onset and regression times.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>15991508</pmid><doi>10.1017/S0265021505000761</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0265-0215 |
| ispartof | European journal of anaesthesiology, 2005-06, Vol.22 (6), p.447-451 |
| issn | 0265-0215 1365-2346 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67992122 |
| source | MEDLINE; Journals@Ovid Ovid Autoload |
| subjects | Adult Analgesics - administration & dosage Analgesics - therapeutic use Analgesics, Opioid - therapeutic use Anesthesia Anesthesia, Conduction Anesthesia, Intravenous Anesthetics, Local - administration & dosage Anesthetics, Local - therapeutic use Blood Pressure - drug effects Dexmedetomidine - administration & dosage Dexmedetomidine - therapeutic use Double-Blind Method Electrocardiography Female Fentanyl - therapeutic use Hand - surgery Hemodynamics - drug effects Humans Lidocaine - administration & dosage Lidocaine - therapeutic use Male Middle Aged Nerve Block Original Article Pain Measurement Pain, Postoperative - drug therapy Prospective Studies Quality Studies Surgery |
| title | Addition of dexmedetomidine to lidocaine for intravenous regional anaesthesia |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T16%3A49%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Addition%20of%20dexmedetomidine%20to%20lidocaine%20for%20intravenous%20regional%20anaesthesia&rft.jtitle=European%20journal%20of%20anaesthesiology&rft.au=Esmaoglu,%20A.&rft.date=2005-06&rft.volume=22&rft.issue=6&rft.spage=447&rft.epage=451&rft.pages=447-451&rft.issn=0265-0215&rft.eissn=1365-2346&rft_id=info:doi/10.1017/S0265021505000761&rft_dat=%3Cproquest_pubme%3E67992122%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=216602264&rft_id=info:pmid/15991508&rft_cupid=10_1017_S0265021505000761&rfr_iscdi=true |