Inhaled nitric oxide enhances distal lung growth after exposure to hyperoxia in neonatal rats

Exposure of newborn rats to hyperoxia impairs alveolarization and vessel growth, causing abnormal lung structure that persists during infancy. Recent studies have shown that impaired angiogenesis due to inhibition of vascular endothelial growth factor (VEGF) signaling decreases alveolar and vessel g...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Pediatric research 2005-07, Vol.58 (1), p.22-29
Hauptverfasser:	Lin, Yuh-Jyh, Markham, Neil E, Balasubramaniam, Vivek, Tang, Jen-Ruey, Maxey, Anne, Kinsella, John P, Abman, Steven H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Blotting, Western Body Weight Hypertrophy Hypoxia - metabolism Immunohistochemistry Lung - metabolism Lung - pathology Lung Injury Nitric Oxide - metabolism Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type III Organ Size Oxygen - metabolism Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction Signal Transduction Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-2 - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!