Proinflammatory cytokine and chemokine modulation by Streptococcus suis in a whole-blood culture system

Abstract Streptococcus suis is an important swine and human pathogen. Inflammation, a hallmark of S. suis infection, is thought to be responsible for most clinical signs of meningitis, septicaemia and sudden death. In this work, using a porcine whole blood model, S. suis serotype 2 was shown to trig...

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Veröffentlicht in:	FEMS immunology and medical microbiology 2006-06, Vol.47 (1), p.92-106
Hauptverfasser:	Segura, Mariela, Vanier, Ghyslaine, Al-Numani, Dina, Lacouture, Sonia, Olivier, Martin, Gottschalk, Marcelo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Bacteria Bacteriology Biological and medical sciences Blood Blood - immunology Blood - microbiology Blood culture Cell culture Cell walls Chemokines Chemokines - biosynthesis Chemokines - genetics Chemokines - immunology Cytokines Cytokines - biosynthesis Cytokines - genetics Cytokines - immunology Cytokines - secretion Enzyme-linked immunosorbent assay Enzyme-Linked Immunosorbent Assay - methods Fundamental and applied biological sciences. Psychology Gene Expression IL-1β Inflammation Inflammation - blood Inflammation - immunology Interleukin 1 Interleukin 6 Interleukin 8 Meningitis Microbiology Miscellaneous Modulation Monocyte chemoattractant protein 1 Monocytes Phagocytosis Phenotypes porcine cytokines Reverse Transcriptase Polymerase Chain Reaction - methods RNA, Messenger - biosynthesis RNA, Messenger - genetics RNA-directed DNA polymerase Streptococcal Infections - blood Streptococcal Infections - immunology Streptococcus infections Streptococcus suis Streptococcus suis - immunology Swine Tumor necrosis factor Tumors virulence factors whole‐blood model
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