Prognostic Significance of Blasts in the Cerebrospinal Fluid Without Pleiocytosis or a Traumatic Lumbar Puncture in Children With Acute Lymphoblastic Leukemia: Experience of the Dutch Childhood Oncology Group

To determine the significance of blasts in the CSF without pleiocytosis and a traumatic lumbar puncture in children with acute lymphoblastic leukemia (ALL). We retrospectively studied a cohort of 526 patients treated in accordance with the virtually identical Dutch protocols ALL-7 and ALL-8. Patient...

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Veröffentlicht in:	Journal of clinical oncology 2006-05, Vol.24 (15), p.2332-2336
Hauptverfasser:	TE LOO, D. Maroeska W. M, KAMPS, Willem A, VAN DER DOES-VAN DEN BERG, Anna, VAN WERING, Elisabeth R, DE GRAAF, Siebold S. N
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Blast Crisis - cerebrospinal fluid Central Nervous System Neoplasms - cerebrospinal fluid Central Nervous System Neoplasms - drug therapy Cerebrospinal Fluid - cytology Child Child, Preschool Cohort Studies Female Follow-Up Studies Hematologic and hematopoietic diseases Humans Infant Infant, Newborn Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphocyte Activation Lymphocyte Count Male Medical sciences Meningeal Neoplasms - cerebrospinal fluid Meningeal Neoplasms - drug therapy Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - etiology Precursor Cell Lymphoblastic Leukemia-Lymphoma - cerebrospinal fluid Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy Precursor Cell Lymphoblastic Leukemia-Lymphoma - pathology Prognosis Retrospective Studies Spinal Puncture - adverse effects Tumors
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