Combined use of SLO microperimetry and OCT for retinal functional and structural testing
This study compared SLO microperimetry scotoma size measurements with the sizes of lesions assessed with OCT in the areas of scotoma. SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the sco...
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| Veröffentlicht in: | Graefe's archive for clinical and experimental ophthalmology 2006-05, Vol.244 (5), p.634-638 |
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| creator | Menke, Marcel N Sato, Eiichi Van De Velde, Frans J Feke, Gilbert T |
| description | This study compared SLO microperimetry scotoma size measurements with the sizes of lesions assessed with OCT in the areas of scotoma.
SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the scotoma areas in the real time OCT fundus image and to center OCT cross scans on the areas of scotoma. The sizes of the morphological changes measured by OCT were compared with the scotoma size measurements.
In each patient, OCT revealed a morphological change located in the area of scotoma. Scotoma sizes ranged from 465 to 3180 microm horizontally and from 570 to 2550 microm vertically. The corresponding lesion sizes ranged from 461 to 2660 microm horizontally and from 523 to 2282 microm vertically. The average difference between SLO and OCT measurements was 2.4% horizontally and 4.9% vertically. There were significant correlations between horizontal and vertical SLO and OCT measurements (Horizontal: R (sq)=0.955, P |
| doi_str_mv | 10.1007/s00417-005-0088-2 |
| format | Article |
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SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the scotoma areas in the real time OCT fundus image and to center OCT cross scans on the areas of scotoma. The sizes of the morphological changes measured by OCT were compared with the scotoma size measurements.
In each patient, OCT revealed a morphological change located in the area of scotoma. Scotoma sizes ranged from 465 to 3180 microm horizontally and from 570 to 2550 microm vertically. The corresponding lesion sizes ranged from 461 to 2660 microm horizontally and from 523 to 2282 microm vertically. The average difference between SLO and OCT measurements was 2.4% horizontally and 4.9% vertically. There were significant correlations between horizontal and vertical SLO and OCT measurements (Horizontal: R (sq)=0.955, P<0.0001; Vertical: R (sq)=0.898, P=0.0003).
SLO microperimetry scotoma size measurements and OCT lesion size measurements are similar to each other. Combining retinal functional testing with morphological testing provides information about the underlying causes of scotoma.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/s00417-005-0088-2</identifier><identifier>PMID: 16133024</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Female ; Humans ; Lasers ; Male ; Ophthalmology ; Ophthalmoscopes ; Retina - physiopathology ; Scotoma - diagnosis ; Scotoma - physiopathology ; Tomography, Optical Coherence - methods ; Visual Field Tests - methods ; Visual Fields - physiology</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 2006-05, Vol.244 (5), p.634-638</ispartof><rights>Springer-Verlag 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-d213414fbfe3c3bcd85740b10d99f89c1be51b3b305f9c7986190a6e51c3639f3</citedby><cites>FETCH-LOGICAL-c326t-d213414fbfe3c3bcd85740b10d99f89c1be51b3b305f9c7986190a6e51c3639f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16133024$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Menke, Marcel N</creatorcontrib><creatorcontrib>Sato, Eiichi</creatorcontrib><creatorcontrib>Van De Velde, Frans J</creatorcontrib><creatorcontrib>Feke, Gilbert T</creatorcontrib><title>Combined use of SLO microperimetry and OCT for retinal functional and structural testing</title><title>Graefe's archive for clinical and experimental ophthalmology</title><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><description>This study compared SLO microperimetry scotoma size measurements with the sizes of lesions assessed with OCT in the areas of scotoma.
SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the scotoma areas in the real time OCT fundus image and to center OCT cross scans on the areas of scotoma. The sizes of the morphological changes measured by OCT were compared with the scotoma size measurements.
In each patient, OCT revealed a morphological change located in the area of scotoma. Scotoma sizes ranged from 465 to 3180 microm horizontally and from 570 to 2550 microm vertically. The corresponding lesion sizes ranged from 461 to 2660 microm horizontally and from 523 to 2282 microm vertically. The average difference between SLO and OCT measurements was 2.4% horizontally and 4.9% vertically. There were significant correlations between horizontal and vertical SLO and OCT measurements (Horizontal: R (sq)=0.955, P<0.0001; Vertical: R (sq)=0.898, P=0.0003).
SLO microperimetry scotoma size measurements and OCT lesion size measurements are similar to each other. Combining retinal functional testing with morphological testing provides information about the underlying causes of scotoma.</description><subject>Female</subject><subject>Humans</subject><subject>Lasers</subject><subject>Male</subject><subject>Ophthalmology</subject><subject>Ophthalmoscopes</subject><subject>Retina - physiopathology</subject><subject>Scotoma - diagnosis</subject><subject>Scotoma - physiopathology</subject><subject>Tomography, Optical Coherence - methods</subject><subject>Visual Field Tests - methods</subject><subject>Visual Fields - physiology</subject><issn>0721-832X</issn><issn>1435-702X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkE1LAzEQhoMotlZ_gBcJHrytTjL7eZTiFxR6sEJvYZNNZMvupiabQ_-9WVoQPIRJJs87IQ8htwweGUDx5AFSViQAWVxlmfAzMmcpZkkBfHtO5lBwlpTItzNy5f0OIo4ZuyQzljNE4OmcbJe2l-2gGxq8ptbQz9Wa9q1ydq9d2-vRHWg9NHS93FBjHXV6bIe6oyYMamzttJ2u_eiCGoOLx1H7iHxfkwtTd17fnOqCfL2-bJbvyWr99rF8XiUKeT4mDWeYstRIo1GhVE2ZFSlIBk1VmbJSTOqMSZQImalUUZU5q6DOY1NhjpXBBXk4zt07-xPi26JvvdJdVw_aBi_ymEkLzCJ4_w_c2eDiB7zgCCVEHWWE2BGKArx32oh9tFC7g2AgJufi6FxE52JyHrMLcncaHGSvm7_ESTL-ApHke-w</recordid><startdate>200605</startdate><enddate>200605</enddate><creator>Menke, Marcel N</creator><creator>Sato, Eiichi</creator><creator>Van De Velde, Frans J</creator><creator>Feke, Gilbert T</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>200605</creationdate><title>Combined use of SLO microperimetry and OCT for retinal functional and structural testing</title><author>Menke, Marcel N ; Sato, Eiichi ; Van De Velde, Frans J ; Feke, Gilbert T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-d213414fbfe3c3bcd85740b10d99f89c1be51b3b305f9c7986190a6e51c3639f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Female</topic><topic>Humans</topic><topic>Lasers</topic><topic>Male</topic><topic>Ophthalmology</topic><topic>Ophthalmoscopes</topic><topic>Retina - physiopathology</topic><topic>Scotoma - diagnosis</topic><topic>Scotoma - physiopathology</topic><topic>Tomography, Optical Coherence - methods</topic><topic>Visual Field Tests - methods</topic><topic>Visual Fields - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Menke, Marcel N</creatorcontrib><creatorcontrib>Sato, Eiichi</creatorcontrib><creatorcontrib>Van De Velde, Frans J</creatorcontrib><creatorcontrib>Feke, Gilbert T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Menke, Marcel N</au><au>Sato, Eiichi</au><au>Van De Velde, Frans J</au><au>Feke, Gilbert T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Combined use of SLO microperimetry and OCT for retinal functional and structural testing</atitle><jtitle>Graefe's archive for clinical and experimental ophthalmology</jtitle><addtitle>Graefes Arch Clin Exp Ophthalmol</addtitle><date>2006-05</date><risdate>2006</risdate><volume>244</volume><issue>5</issue><spage>634</spage><epage>638</epage><pages>634-638</pages><issn>0721-832X</issn><eissn>1435-702X</eissn><abstract>This study compared SLO microperimetry scotoma size measurements with the sizes of lesions assessed with OCT in the areas of scotoma.
SLO microperimetry was performed on eight patients to assess the location and extent of scotoma areas. An SLO microperimetry master image was used to localize the scotoma areas in the real time OCT fundus image and to center OCT cross scans on the areas of scotoma. The sizes of the morphological changes measured by OCT were compared with the scotoma size measurements.
In each patient, OCT revealed a morphological change located in the area of scotoma. Scotoma sizes ranged from 465 to 3180 microm horizontally and from 570 to 2550 microm vertically. The corresponding lesion sizes ranged from 461 to 2660 microm horizontally and from 523 to 2282 microm vertically. The average difference between SLO and OCT measurements was 2.4% horizontally and 4.9% vertically. There were significant correlations between horizontal and vertical SLO and OCT measurements (Horizontal: R (sq)=0.955, P<0.0001; Vertical: R (sq)=0.898, P=0.0003).
SLO microperimetry scotoma size measurements and OCT lesion size measurements are similar to each other. Combining retinal functional testing with morphological testing provides information about the underlying causes of scotoma.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>16133024</pmid><doi>10.1007/s00417-005-0088-2</doi><tpages>5</tpages></addata></record> |
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| subjects | Female Humans Lasers Male Ophthalmology Ophthalmoscopes Retina - physiopathology Scotoma - diagnosis Scotoma - physiopathology Tomography, Optical Coherence - methods Visual Field Tests - methods Visual Fields - physiology |
| title | Combined use of SLO microperimetry and OCT for retinal functional and structural testing |
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