Analysis of skin-graft loss due to infection : Infection-related graft loss
This prospective study was performed to analyze the causes of infection-related skin-graft loss in a general population of plastic and reconstructive surgery patients. One hundred thirty-two patients who received either full- or split-thickness skin grafts to reconstruct soft-tissue defects were inc...
Gespeichert in:
| Veröffentlicht in: | Annals of plastic surgery 2005-07, Vol.55 (1), p.102-106 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 106 |
|---|---|
| container_issue | 1 |
| container_start_page | 102 |
| container_title | Annals of plastic surgery |
| container_volume | 55 |
| creator | ÜNAL, Sakir ERSOZ, Gulden DEMIRKAN, Ferit ARSLAN, Emrah TÜTÜNCÜ, Necmettin SARI, Alper |
| description | This prospective study was performed to analyze the causes of infection-related skin-graft loss in a general population of plastic and reconstructive surgery patients. One hundred thirty-two patients who received either full- or split-thickness skin grafts to reconstruct soft-tissue defects were included. The tissue defects were grouped according to the cause as follows: vascular ulcers (9.2%), burns (14.5%), traumatic tissue defects (36.6%), and flap donor-site defects (39.7%). In all cases, the preoperative evaluation indicated an adequate wound-bed preparation. However, graft loss secondary to infection was recorded in 31 patients (23.5%). The microbiological cultures revealed Pseudomonas aeruginosa in 58.1% of the cases (P |
| doi_str_mv | 10.1097/01.sap.0000164531.23770.60 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67982808</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67982808</sourcerecordid><originalsourceid>FETCH-LOGICAL-c290t-318f45458d2d573d382291afdff4b772a32c8b41ab10a40bbadbfc81cfcfae373</originalsourceid><addsrcrecordid>eNpFkMtOwzAQRS0EoqXwC8hCgl3C-JHY6a6qeFRUYgNry3FsFEiTYieL_j2GBmU2M4tzZ0YHoRsCKYFC3ANJg96nEIvkPGMkpUwISHM4QXOSsTxhAuQpmgPhMhHA2QxdhPAZcSp5fo5mJCtkJoHM0cuq1c0h1AF3Doevuk0-vHY9broQcDVY3He4bp01fd21eIk3_3PibaN7W-GJv0RnTjfBXo19gd4fH97Wz8n29WmzXm0TQwvoE0ak4xnPZEWrTLCKSUoLol3lHC-FoJpRI0tOdElAcyhLXZXOSGKccdoywRbo7rh377vvwYZe7epgbNPo1nZDULkoJJUgI7g8gsbH97x1au_rnfYHRUD9qlRAVFSpJpXqT6XKIYavxytDubPVFB3dReB2BHQwunFet6YOEyeibioF-wG58H2t</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67982808</pqid></control><display><type>article</type><title>Analysis of skin-graft loss due to infection : Infection-related graft loss</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>ÜNAL, Sakir ; ERSOZ, Gulden ; DEMIRKAN, Ferit ; ARSLAN, Emrah ; TÜTÜNCÜ, Necmettin ; SARI, Alper</creator><creatorcontrib>ÜNAL, Sakir ; ERSOZ, Gulden ; DEMIRKAN, Ferit ; ARSLAN, Emrah ; TÜTÜNCÜ, Necmettin ; SARI, Alper</creatorcontrib><description>This prospective study was performed to analyze the causes of infection-related skin-graft loss in a general population of plastic and reconstructive surgery patients. One hundred thirty-two patients who received either full- or split-thickness skin grafts to reconstruct soft-tissue defects were included. The tissue defects were grouped according to the cause as follows: vascular ulcers (9.2%), burns (14.5%), traumatic tissue defects (36.6%), and flap donor-site defects (39.7%). In all cases, the preoperative evaluation indicated an adequate wound-bed preparation. However, graft loss secondary to infection was recorded in 31 patients (23.5%). The microbiological cultures revealed Pseudomonas aeruginosa in 58.1% of the cases (P<0.05), followed by Staphylococcus aureus, Enterobacter, enterococci, and Acinetobacter; 58.3% of grafts in vascular ulcers, 47.4% of grafts in burns, 16.7% of grafts in traumatic-tissue defects; and 13.5% of grafts in donor-site defects were lost due to infection. Vascular ulcers and burns were more commonly associated with graft losses due to infection than other tissue defects (P<0.001). No correlation was found between the etiological cause of the defects and the microorganisms cultured. However, Pseudomonas infections were more fulminant and caused an increased reoperation rate 4.2 times (P<0.05). Full-thickness grafts were more resistant to infection than split-thickness grafts (P<0.05). Graft loss due to infection was also more common in grafts applied to the lower extremities or when performed at multiple sites. In conclusion, 23.7% of skin grafts were lost due to infection in a group of general plastic surgery patients. Infection-related graft loss was more commonly encountered in vascular ulcers and burn wounds, and the most common cause was Pseudomonas aeruginosa.</description><identifier>ISSN: 0148-7043</identifier><identifier>EISSN: 1536-3708</identifier><identifier>DOI: 10.1097/01.sap.0000164531.23770.60</identifier><identifier>PMID: 15985801</identifier><identifier>CODEN: APCSD4</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Biological and medical sciences ; Chi-Square Distribution ; Female ; Graft Survival ; Humans ; Logistic Models ; Male ; Medical sciences ; Prospective Studies ; Skin Transplantation ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgical Wound Infection - etiology ; Surgical Wound Infection - microbiology</subject><ispartof>Annals of plastic surgery, 2005-07, Vol.55 (1), p.102-106</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c290t-318f45458d2d573d382291afdff4b772a32c8b41ab10a40bbadbfc81cfcfae373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17012287$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15985801$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ÜNAL, Sakir</creatorcontrib><creatorcontrib>ERSOZ, Gulden</creatorcontrib><creatorcontrib>DEMIRKAN, Ferit</creatorcontrib><creatorcontrib>ARSLAN, Emrah</creatorcontrib><creatorcontrib>TÜTÜNCÜ, Necmettin</creatorcontrib><creatorcontrib>SARI, Alper</creatorcontrib><title>Analysis of skin-graft loss due to infection : Infection-related graft loss</title><title>Annals of plastic surgery</title><addtitle>Ann Plast Surg</addtitle><description>This prospective study was performed to analyze the causes of infection-related skin-graft loss in a general population of plastic and reconstructive surgery patients. One hundred thirty-two patients who received either full- or split-thickness skin grafts to reconstruct soft-tissue defects were included. The tissue defects were grouped according to the cause as follows: vascular ulcers (9.2%), burns (14.5%), traumatic tissue defects (36.6%), and flap donor-site defects (39.7%). In all cases, the preoperative evaluation indicated an adequate wound-bed preparation. However, graft loss secondary to infection was recorded in 31 patients (23.5%). The microbiological cultures revealed Pseudomonas aeruginosa in 58.1% of the cases (P<0.05), followed by Staphylococcus aureus, Enterobacter, enterococci, and Acinetobacter; 58.3% of grafts in vascular ulcers, 47.4% of grafts in burns, 16.7% of grafts in traumatic-tissue defects; and 13.5% of grafts in donor-site defects were lost due to infection. Vascular ulcers and burns were more commonly associated with graft losses due to infection than other tissue defects (P<0.001). No correlation was found between the etiological cause of the defects and the microorganisms cultured. However, Pseudomonas infections were more fulminant and caused an increased reoperation rate 4.2 times (P<0.05). Full-thickness grafts were more resistant to infection than split-thickness grafts (P<0.05). Graft loss due to infection was also more common in grafts applied to the lower extremities or when performed at multiple sites. In conclusion, 23.7% of skin grafts were lost due to infection in a group of general plastic surgery patients. Infection-related graft loss was more commonly encountered in vascular ulcers and burn wounds, and the most common cause was Pseudomonas aeruginosa.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Chi-Square Distribution</subject><subject>Female</subject><subject>Graft Survival</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Prospective Studies</subject><subject>Skin Transplantation</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgical Wound Infection - etiology</subject><subject>Surgical Wound Infection - microbiology</subject><issn>0148-7043</issn><issn>1536-3708</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtOwzAQRS0EoqXwC8hCgl3C-JHY6a6qeFRUYgNry3FsFEiTYieL_j2GBmU2M4tzZ0YHoRsCKYFC3ANJg96nEIvkPGMkpUwISHM4QXOSsTxhAuQpmgPhMhHA2QxdhPAZcSp5fo5mJCtkJoHM0cuq1c0h1AF3Doevuk0-vHY9broQcDVY3He4bp01fd21eIk3_3PibaN7W-GJv0RnTjfBXo19gd4fH97Wz8n29WmzXm0TQwvoE0ak4xnPZEWrTLCKSUoLol3lHC-FoJpRI0tOdElAcyhLXZXOSGKccdoywRbo7rh377vvwYZe7epgbNPo1nZDULkoJJUgI7g8gsbH97x1au_rnfYHRUD9qlRAVFSpJpXqT6XKIYavxytDubPVFB3dReB2BHQwunFet6YOEyeibioF-wG58H2t</recordid><startdate>20050701</startdate><enddate>20050701</enddate><creator>ÜNAL, Sakir</creator><creator>ERSOZ, Gulden</creator><creator>DEMIRKAN, Ferit</creator><creator>ARSLAN, Emrah</creator><creator>TÜTÜNCÜ, Necmettin</creator><creator>SARI, Alper</creator><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050701</creationdate><title>Analysis of skin-graft loss due to infection : Infection-related graft loss</title><author>ÜNAL, Sakir ; ERSOZ, Gulden ; DEMIRKAN, Ferit ; ARSLAN, Emrah ; TÜTÜNCÜ, Necmettin ; SARI, Alper</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c290t-318f45458d2d573d382291afdff4b772a32c8b41ab10a40bbadbfc81cfcfae373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Chi-Square Distribution</topic><topic>Female</topic><topic>Graft Survival</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Prospective Studies</topic><topic>Skin Transplantation</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgical Wound Infection - etiology</topic><topic>Surgical Wound Infection - microbiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>ÜNAL, Sakir</creatorcontrib><creatorcontrib>ERSOZ, Gulden</creatorcontrib><creatorcontrib>DEMIRKAN, Ferit</creatorcontrib><creatorcontrib>ARSLAN, Emrah</creatorcontrib><creatorcontrib>TÜTÜNCÜ, Necmettin</creatorcontrib><creatorcontrib>SARI, Alper</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Annals of plastic surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ÜNAL, Sakir</au><au>ERSOZ, Gulden</au><au>DEMIRKAN, Ferit</au><au>ARSLAN, Emrah</au><au>TÜTÜNCÜ, Necmettin</au><au>SARI, Alper</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of skin-graft loss due to infection : Infection-related graft loss</atitle><jtitle>Annals of plastic surgery</jtitle><addtitle>Ann Plast Surg</addtitle><date>2005-07-01</date><risdate>2005</risdate><volume>55</volume><issue>1</issue><spage>102</spage><epage>106</epage><pages>102-106</pages><issn>0148-7043</issn><eissn>1536-3708</eissn><coden>APCSD4</coden><abstract>This prospective study was performed to analyze the causes of infection-related skin-graft loss in a general population of plastic and reconstructive surgery patients. One hundred thirty-two patients who received either full- or split-thickness skin grafts to reconstruct soft-tissue defects were included. The tissue defects were grouped according to the cause as follows: vascular ulcers (9.2%), burns (14.5%), traumatic tissue defects (36.6%), and flap donor-site defects (39.7%). In all cases, the preoperative evaluation indicated an adequate wound-bed preparation. However, graft loss secondary to infection was recorded in 31 patients (23.5%). The microbiological cultures revealed Pseudomonas aeruginosa in 58.1% of the cases (P<0.05), followed by Staphylococcus aureus, Enterobacter, enterococci, and Acinetobacter; 58.3% of grafts in vascular ulcers, 47.4% of grafts in burns, 16.7% of grafts in traumatic-tissue defects; and 13.5% of grafts in donor-site defects were lost due to infection. Vascular ulcers and burns were more commonly associated with graft losses due to infection than other tissue defects (P<0.001). No correlation was found between the etiological cause of the defects and the microorganisms cultured. However, Pseudomonas infections were more fulminant and caused an increased reoperation rate 4.2 times (P<0.05). Full-thickness grafts were more resistant to infection than split-thickness grafts (P<0.05). Graft loss due to infection was also more common in grafts applied to the lower extremities or when performed at multiple sites. In conclusion, 23.7% of skin grafts were lost due to infection in a group of general plastic surgery patients. Infection-related graft loss was more commonly encountered in vascular ulcers and burn wounds, and the most common cause was Pseudomonas aeruginosa.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins</pub><pmid>15985801</pmid><doi>10.1097/01.sap.0000164531.23770.60</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-7043 |
| ispartof | Annals of plastic surgery, 2005-07, Vol.55 (1), p.102-106 |
| issn | 0148-7043 1536-3708 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67982808 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Adult Biological and medical sciences Chi-Square Distribution Female Graft Survival Humans Logistic Models Male Medical sciences Prospective Studies Skin Transplantation Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical Wound Infection - etiology Surgical Wound Infection - microbiology |
| title | Analysis of skin-graft loss due to infection : Infection-related graft loss |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T14%3A29%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Analysis%20of%20skin-graft%20loss%20due%20to%20infection%20:%20Infection-related%20graft%20loss&rft.jtitle=Annals%20of%20plastic%20surgery&rft.au=%C3%9CNAL,%20Sakir&rft.date=2005-07-01&rft.volume=55&rft.issue=1&rft.spage=102&rft.epage=106&rft.pages=102-106&rft.issn=0148-7043&rft.eissn=1536-3708&rft.coden=APCSD4&rft_id=info:doi/10.1097/01.sap.0000164531.23770.60&rft_dat=%3Cproquest_cross%3E67982808%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67982808&rft_id=info:pmid/15985801&rfr_iscdi=true |