Inhibitory action of eugenol compounds on the production of nitric oxide in RAW264.7 macrophages

Effects of eugenol compounds on the production of nitric oxide (NO) in RAW264.7 macrophages were analyzed in relation to the anti-inflammatory action of these compounds. Eugenol and isoeugenol inhibited lipopolysaccharide (LPS)-dependent production of NO, which was due to the inhibition of protein s...

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Veröffentlicht in:	Biomedical Research 2006, Vol.27(2), pp.69-74
Hauptverfasser:	LI, Weihua, TSUBOUCHI, Ryoko, QIAO, Shanlou, HANEDA, Miyako, MURAKAMI, Keiko, YOSHINO, Masataka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - chemistry Anti-Inflammatory Agents - pharmacology Cell Line Cyclooxygenase 2 - metabolism Eugenol - chemistry Eugenol - pharmacology Inflammation - metabolism Lipopolysaccharides - pharmacology Macrophages - cytology Macrophages - drug effects Macrophages - metabolism Mice Nitric Oxide - biosynthesis Nitric Oxide Synthase Type II - antagonists & inhibitors Nitric Oxide Synthase Type II - metabolism Superoxide Dismutase - metabolism
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