Fecal fungal flora of pediatric healthy volunteers and immunosuppressed patients
Most hematogenous candidiasis originates from endogeneous host flora. Fungal flora of gastrointestinal system are important source of infection especially in immunosupressed patients. The purpose of this study was to investigate the fecal fungal flora of pediatric patients with hematologic malignanc...
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| Veröffentlicht in: | Mycopathologia (1975) 2005-06, Vol.159 (4), p.515-520 |
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| creator | Agirbasli, H Ozcan, S A Keceli Gedikoğlu, Gündüz |
| description | Most hematogenous candidiasis originates from endogeneous host flora. Fungal flora of gastrointestinal system are important source of infection especially in immunosupressed patients. The purpose of this study was to investigate the fecal fungal flora of pediatric patients with hematologic malignancy or disorders and to compare the results with healthy volunteers. For this purpose, fungal etiological agents were investigated retrospectively in stool samples of 80 patients followed in Bone marrow transplantation and Hematology-Oncology units. The diagnosis of patients were as follows: 26 acute myelogeneous leukemia, 19 acute lymphocytic leukemia, 5 lymphoma, 3 chronic myelogeneous leukemia, 2 solid tumor, 4 neuroblastoma and 21 hematologic disorders. In patients, totally 102 fungal growth was detected and 42 (41.2%) C. albicans and 51 (50%) non-albicans Candida species and 9 (8.8%) yeast other than Candida and mould was isolated. The results were compared prospectively with growth in stool samples of 61 healthy children. C. albicans was detected in 16 (43.2%) and non-albicans Candida species in 15 (40.5%) and yeasts other than Candida and mould in 6 (16.2%) of 37 fungal growth in controls. Non-albicans Candida species growth was found significantly higher and C. glabrata was more prevelant in patients than in controls (p < 0.001). |
| doi_str_mv | 10.1007/s11046-005-3451-2 |
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Fungal flora of gastrointestinal system are important source of infection especially in immunosupressed patients. The purpose of this study was to investigate the fecal fungal flora of pediatric patients with hematologic malignancy or disorders and to compare the results with healthy volunteers. For this purpose, fungal etiological agents were investigated retrospectively in stool samples of 80 patients followed in Bone marrow transplantation and Hematology-Oncology units. The diagnosis of patients were as follows: 26 acute myelogeneous leukemia, 19 acute lymphocytic leukemia, 5 lymphoma, 3 chronic myelogeneous leukemia, 2 solid tumor, 4 neuroblastoma and 21 hematologic disorders. In patients, totally 102 fungal growth was detected and 42 (41.2%) C. albicans and 51 (50%) non-albicans Candida species and 9 (8.8%) yeast other than Candida and mould was isolated. The results were compared prospectively with growth in stool samples of 61 healthy children. C. albicans was detected in 16 (43.2%) and non-albicans Candida species in 15 (40.5%) and yeasts other than Candida and mould in 6 (16.2%) of 37 fungal growth in controls. Non-albicans Candida species growth was found significantly higher and C. glabrata was more prevelant in patients than in controls (p < 0.001).</description><identifier>ISSN: 0301-486X</identifier><identifier>EISSN: 1573-0832</identifier><identifier>DOI: 10.1007/s11046-005-3451-2</identifier><identifier>PMID: 15983737</identifier><language>eng</language><publisher>Netherlands: Springer Nature B.V</publisher><subject>Adolescent ; Adult ; Antibiotics ; Bacterial infections ; Blood diseases ; Bone marrow ; Bone Marrow Transplantation ; Candida ; Candida - isolation & purification ; Candidiasis - immunology ; Candidiasis - microbiology ; Child ; Child, Preschool ; Disease prevention ; Feces ; Feces - microbiology ; Female ; Hematologic Diseases - immunology ; Hematologic Diseases - microbiology ; Hematology ; Hospitalization ; Humans ; Immunocompromised Host ; Infant ; Leukemia ; Male ; Mold ; Morphology ; Nosocomial infections ; Oncology ; Pediatrics ; Retrospective Studies ; Statistics, Nonparametric ; Stem cell transplantation</subject><ispartof>Mycopathologia (1975), 2005-06, Vol.159 (4), p.515-520</ispartof><rights>Springer 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c357t-973c2beab2da4d5a14f3d8536e763beaf2871d92d3bcbb7a739bdab232827923</citedby><cites>FETCH-LOGICAL-c357t-973c2beab2da4d5a14f3d8536e763beaf2871d92d3bcbb7a739bdab232827923</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15983737$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Agirbasli, H</creatorcontrib><creatorcontrib>Ozcan, S A Keceli</creatorcontrib><creatorcontrib>Gedikoğlu, Gündüz</creatorcontrib><title>Fecal fungal flora of pediatric healthy volunteers and immunosuppressed patients</title><title>Mycopathologia (1975)</title><addtitle>Mycopathologia</addtitle><description>Most hematogenous candidiasis originates from endogeneous host flora. Fungal flora of gastrointestinal system are important source of infection especially in immunosupressed patients. The purpose of this study was to investigate the fecal fungal flora of pediatric patients with hematologic malignancy or disorders and to compare the results with healthy volunteers. For this purpose, fungal etiological agents were investigated retrospectively in stool samples of 80 patients followed in Bone marrow transplantation and Hematology-Oncology units. The diagnosis of patients were as follows: 26 acute myelogeneous leukemia, 19 acute lymphocytic leukemia, 5 lymphoma, 3 chronic myelogeneous leukemia, 2 solid tumor, 4 neuroblastoma and 21 hematologic disorders. In patients, totally 102 fungal growth was detected and 42 (41.2%) C. albicans and 51 (50%) non-albicans Candida species and 9 (8.8%) yeast other than Candida and mould was isolated. The results were compared prospectively with growth in stool samples of 61 healthy children. C. albicans was detected in 16 (43.2%) and non-albicans Candida species in 15 (40.5%) and yeasts other than Candida and mould in 6 (16.2%) of 37 fungal growth in controls. Non-albicans Candida species growth was found significantly higher and C. glabrata was more prevelant in patients than in controls (p < 0.001).</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antibiotics</subject><subject>Bacterial infections</subject><subject>Blood diseases</subject><subject>Bone marrow</subject><subject>Bone Marrow Transplantation</subject><subject>Candida</subject><subject>Candida - isolation & purification</subject><subject>Candidiasis - immunology</subject><subject>Candidiasis - microbiology</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Disease prevention</subject><subject>Feces</subject><subject>Feces - microbiology</subject><subject>Female</subject><subject>Hematologic Diseases - immunology</subject><subject>Hematologic Diseases - microbiology</subject><subject>Hematology</subject><subject>Hospitalization</subject><subject>Humans</subject><subject>Immunocompromised Host</subject><subject>Infant</subject><subject>Leukemia</subject><subject>Male</subject><subject>Mold</subject><subject>Morphology</subject><subject>Nosocomial infections</subject><subject>Oncology</subject><subject>Pediatrics</subject><subject>Retrospective Studies</subject><subject>Statistics, Nonparametric</subject><subject>Stem cell transplantation</subject><issn>0301-486X</issn><issn>1573-0832</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1LxDAQhoMo7rr6A7xI8eAtmsm0TXKUxVVhQQ978BbSJnW79MukFfbf27ILghdPA8MzLzPzEHIN7B4YEw8BgMUpZSyhGCdA-QmZQyKQMon8lMwZMqCxTD9m5CKEHWPjFIhzMoNESRQo5uR95XJTRcXQfE6lar2J2iLqnC1N78s82jpT9dt99N1WQ9M750NkGhuVdT00bRi6zrsQnI0605eu6cMlOStMFdzVsS7IZvW0Wb7Q9dvz6_JxTXNMRE-VwJxnzmTcmtgmBuICrUwwdSLFsV9wKcAqbjHLs0wYgSqzI41ccqE4LsjdIbbz7dfgQq_rMuSuqkzj2iHoVCgJcRr_C4IYnyK5HMHbP-CuHXwz3qA5B-BK4ZQGByj3bQjeFbrzZW38XgPTkxN9cKJHJ3pyoqdVb47BQ1Y7-ztxlIA_lCmH2A</recordid><startdate>200506</startdate><enddate>200506</enddate><creator>Agirbasli, H</creator><creator>Ozcan, S A Keceli</creator><creator>Gedikoğlu, Gündüz</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>200506</creationdate><title>Fecal fungal flora of pediatric healthy volunteers and immunosuppressed patients</title><author>Agirbasli, H ; Ozcan, S A Keceli ; Gedikoğlu, Gündüz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c357t-973c2beab2da4d5a14f3d8536e763beaf2871d92d3bcbb7a739bdab232827923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Antibiotics</topic><topic>Bacterial infections</topic><topic>Blood diseases</topic><topic>Bone marrow</topic><topic>Bone Marrow Transplantation</topic><topic>Candida</topic><topic>Candida - isolation & purification</topic><topic>Candidiasis - immunology</topic><topic>Candidiasis - microbiology</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Disease prevention</topic><topic>Feces</topic><topic>Feces - microbiology</topic><topic>Female</topic><topic>Hematologic Diseases - immunology</topic><topic>Hematologic Diseases - microbiology</topic><topic>Hematology</topic><topic>Hospitalization</topic><topic>Humans</topic><topic>Immunocompromised Host</topic><topic>Infant</topic><topic>Leukemia</topic><topic>Male</topic><topic>Mold</topic><topic>Morphology</topic><topic>Nosocomial infections</topic><topic>Oncology</topic><topic>Pediatrics</topic><topic>Retrospective Studies</topic><topic>Statistics, Nonparametric</topic><topic>Stem cell transplantation</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Agirbasli, H</creatorcontrib><creatorcontrib>Ozcan, S A Keceli</creatorcontrib><creatorcontrib>Gedikoğlu, Gündüz</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Mycopathologia (1975)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Agirbasli, H</au><au>Ozcan, S A Keceli</au><au>Gedikoğlu, Gündüz</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fecal fungal flora of pediatric healthy volunteers and immunosuppressed patients</atitle><jtitle>Mycopathologia (1975)</jtitle><addtitle>Mycopathologia</addtitle><date>2005-06</date><risdate>2005</risdate><volume>159</volume><issue>4</issue><spage>515</spage><epage>520</epage><pages>515-520</pages><issn>0301-486X</issn><eissn>1573-0832</eissn><abstract>Most hematogenous candidiasis originates from endogeneous host flora. Fungal flora of gastrointestinal system are important source of infection especially in immunosupressed patients. The purpose of this study was to investigate the fecal fungal flora of pediatric patients with hematologic malignancy or disorders and to compare the results with healthy volunteers. For this purpose, fungal etiological agents were investigated retrospectively in stool samples of 80 patients followed in Bone marrow transplantation and Hematology-Oncology units. The diagnosis of patients were as follows: 26 acute myelogeneous leukemia, 19 acute lymphocytic leukemia, 5 lymphoma, 3 chronic myelogeneous leukemia, 2 solid tumor, 4 neuroblastoma and 21 hematologic disorders. In patients, totally 102 fungal growth was detected and 42 (41.2%) C. albicans and 51 (50%) non-albicans Candida species and 9 (8.8%) yeast other than Candida and mould was isolated. The results were compared prospectively with growth in stool samples of 61 healthy children. C. albicans was detected in 16 (43.2%) and non-albicans Candida species in 15 (40.5%) and yeasts other than Candida and mould in 6 (16.2%) of 37 fungal growth in controls. Non-albicans Candida species growth was found significantly higher and C. glabrata was more prevelant in patients than in controls (p < 0.001).</abstract><cop>Netherlands</cop><pub>Springer Nature B.V</pub><pmid>15983737</pmid><doi>10.1007/s11046-005-3451-2</doi><tpages>6</tpages></addata></record> |
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| ispartof | Mycopathologia (1975), 2005-06, Vol.159 (4), p.515-520 |
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| subjects | Adolescent Adult Antibiotics Bacterial infections Blood diseases Bone marrow Bone Marrow Transplantation Candida Candida - isolation & purification Candidiasis - immunology Candidiasis - microbiology Child Child, Preschool Disease prevention Feces Feces - microbiology Female Hematologic Diseases - immunology Hematologic Diseases - microbiology Hematology Hospitalization Humans Immunocompromised Host Infant Leukemia Male Mold Morphology Nosocomial infections Oncology Pediatrics Retrospective Studies Statistics, Nonparametric Stem cell transplantation |
| title | Fecal fungal flora of pediatric healthy volunteers and immunosuppressed patients |
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