p63-Specific Activation of the BPAG-1e Promoter

p63, a member of the p53 superfamily, is an essential cell fate determinant for stratified epithelium. Deficiency of p63 leads to lack of differentiated epithelium from the skin and the presence of trace undifferentiated cells left in the dermis. We found that transcriptionally active isoforms of p6...

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Veröffentlicht in:	Journal of investigative dermatology 2005-07, Vol.125 (1), p.52-60
Hauptverfasser:	Osada, Motonobu, Nagakawa, Yuichi, Park, Hannah Lui, Yamashita, Keishi, Wu, Guojun, Sook Kim, Myoung, Fomenkov, Alexey, Trink, Barry, Sidransky, David
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences BPAG-1 Carrier Proteins - metabolism Cytoskeletal Proteins - metabolism Dermatology DNA-Binding Proteins Dystonin Epithelium - metabolism Gene Expression Regulation Genes, Tumor Suppressor Immunohistochemistry Medical sciences Mice Nerve Tissue Proteins - metabolism p53 p53-response element p63 Phosphoproteins - metabolism Promoter Regions, Genetic Trans-Activators - metabolism Transcription Factors Transcriptional Activation Tumor Suppressor Proteins
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