Minireview: Ribonucleic Acid Interference for the Identification of New Targets for the Treatment of Metabolic Diseases

Over the past years, RNA interference (RNAi) has exploded as a new approach to manipulate gene expression in mammalian systems. More recently, RNAi has acquired interest as a tool to identify new targets for therapeutic intervention. This review focuses on the current understanding of RNAi biology,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Endocrinology (Philadelphia) 2006-06, Vol.147 (6), p.2650-2656
1. Verfasser:	Rondinone, Cristina M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoviridae - genetics Agouti-Related Protein Animals Apolipoproteins B - genetics Biological and medical sciences Diabetes mellitus Diabetes Mellitus - therapy Drug development Early Growth Response Protein 1 - genetics Fundamental and applied biological sciences. Psychology Gene expression Humans In vivo methods and tests Insulin - physiology Insulin Receptor Substrate Proteins Intercellular Signaling Peptides and Proteins Metabolic disorders Obesity - therapy Pathogenesis Phosphoproteins - genetics Proteins - genetics RNA Interference RNA-mediated interference Signal Transduction Target acquisition Target recognition Transcription Factors - genetics Vertebrates: endocrinology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!