An unusual complication of cancer treatment for acute lymphoblastic leukemia

Childhood cancer is a leading cause of mortality in children less than 15 years of age, accounting for about 10.4 of total childhood deaths [Robinson LL: In: Pizzo PA, Polack DA (eds) Principles and Practice of Pediatric Oncology, 3rd edn. Lippincott--Raven, Philadelphia--NewYork, 1997, pp. 1-10.]....

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Veröffentlicht in:Journal of neuro-oncology 2005-07, Vol.73 (3), p.269-272
Hauptverfasser: RIEL-ROMERO, Rosario Maria S, BAUMANN, Robert J, SMITH, Charles D
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container_title Journal of neuro-oncology
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creator RIEL-ROMERO, Rosario Maria S
BAUMANN, Robert J
SMITH, Charles D
description Childhood cancer is a leading cause of mortality in children less than 15 years of age, accounting for about 10.4 of total childhood deaths [Robinson LL: In: Pizzo PA, Polack DA (eds) Principles and Practice of Pediatric Oncology, 3rd edn. Lippincott--Raven, Philadelphia--NewYork, 1997, pp. 1-10.]. As more aggressive therapeutic regimens have been adopted and ostensibly cured patients are being followed for longer periods of time, it has become increasingly clear that the treatment of cancer can have significant late effects on the growing child, one of the more troublesome of which is the induction of secondary malignancy. We report an 11-year-old child who, as supported by both clinical course and neuroimaging studies, developed an unusual complication eight years after completing therapy for acute lymphoblastic leukemia, gliomatosis cerebri.
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subjects Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Blood. Blood coagulation. Reticuloendothelial system
Brain Neoplasms - etiology
Brain Neoplasms - pathology
Brain Neoplasms - physiopathology
Child
Female
Humans
Magnetic Resonance Imaging
Medical sciences
Neoplasms, Neuroepithelial - etiology
Neoplasms, Neuroepithelial - pathology
Neoplasms, Neuroepithelial - physiopathology
Neoplasms, Second Primary - etiology
Neoplasms, Second Primary - pathology
Neoplasms, Second Primary - physiopathology
Neurology
Pharmacology. Drug treatments
Pneumology
Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy
Precursor Cell Lymphoblastic Leukemia-Lymphoma - radiotherapy
Tumors of the respiratory system and mediastinum
title An unusual complication of cancer treatment for acute lymphoblastic leukemia
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