Peripheral lipopolysaccharide administration impairs two-way active avoidance conditioning in C57BL/6J mice

Peripheral administration of lipopolysaccharide (LPS) or interleukin-1 (IL-1) may lead to alterations of CNS function and behavioral changes designated “sickness behavior.” Further, some experiments show evidence of LPS- and cytokine-mediated alterations in learning and memory. The current series of...

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Veröffentlicht in:	Physiology & behavior 2005-06, Vol.85 (3), p.278-288
Hauptverfasser:	Sparkman, Nathan L., Kohman, Rachel A., Garcia, Anya K., Boehm, Gary W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Animals Avoidance Learning - drug effects Behavior, Animal - drug effects Biological and medical sciences Conditioning (Psychology) - drug effects Cytokine Dose-Response Relationship, Drug Drug Administration Schedule Endotoxin Escape Reaction - drug effects Fear conditioning Fundamental and applied biological sciences. Psychology IL-1β Interleukin-1β Learning Learning. Memory Lipopolysaccharide Lipopolysaccharides - administration & dosage LPS Male Memory Mice Mice, Inbred C57BL - physiology Negative reinforcement Operant conditioning Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Shuttlebox Time Factors Weight Loss - drug effects
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