Analysis of c-kit expression in small cell lung cancer: Prevalence and prognostic implications

c-kit, a growth factor receptor with tyrosine kinase activity, plays an important role in the biology of cancer. Its expression has been documented in several malignancies. We performed a retrospective study in 85 patients diagnosed with small cell lung cancer (SCLC) to determine the prevalence and...

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Veröffentlicht in:	Lung cancer (Amsterdam, Netherlands) Netherlands), 2006-06, Vol.52 (3), p.343-347
Hauptverfasser:	Camps, Carlos, Sirera, Rafael, Bremnes, Roy M., Garde, Javier, Safont, María José, Blasco, Ana, Berrocal, Alfonso, Sánchez, José Javier, Calabuig, Consuelo, Martorell, Miguel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Combined Chemotherapy Protocols - administration & dosage Biological and medical sciences Biomarkers, Tumor - biosynthesis c-kit Carcinoma, Small Cell - drug therapy Carcinoma, Small Cell - metabolism Carcinoma, Small Cell - mortality Female Gene Expression Regulation, Neoplastic Humans Lung Neoplasms - drug therapy Lung Neoplasms - metabolism Lung Neoplasms - mortality Male Medical sciences Molecular markers Pneumology Predictive Value of Tests Prevalence Prognosis Prognostic factors Proto-Oncogene Proteins c-kit - biosynthesis Retrospective Studies Small cell lung cancer (SCLC) Survival Rate Tumors of the respiratory system and mediastinum
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