Use of micro-rotation imaging to study JNK-mediated cell survival in Theileria parva-infected B-lymphocytes

Lymphocytes infected with the protozoan parasite Theileria parva are transformed to permanently proliferating cells, an event underlying the pathology of the disease. However, the molecular signalling mediating this process is complex and poorly understood. Here, we show that down-regulation of JNK...

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Veröffentlicht in:	Parasitology 2005-06, Vol.130 (6), p.629-635
Hauptverfasser:	LIZUNDIA, R., SENGMANIVONG, L., GUERGNON, J., MÜLLER, T., SCHNELLE, T., LANGSLEY, G., SHORTE, S. L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Apoptosis - physiology B-lymphocyte B-lymphocytes B-Lymphocytes - parasitology B-Lymphocytes - ultrastructure Biological and medical sciences Cells chromatin Chromatin - physiology Clone Cells Diagnostic Imaging - methods Enzyme Activation flow cytometry Fundamental and applied biological sciences. Psychology gene expression regulation gene overexpression General aspects General aspects and techniques. Study of several systematic groups. Models green fluorescent protein image analysis infection Invertebrates JNK JNK Mitogen-Activated Protein Kinases - genetics JNK Mitogen-Activated Protein Kinases - physiology Kinases labeling techniques Lymphocytes micro-rotation imaging mitogen-activated protein kinase Mutation Parasites protein kinases Signal Transduction single cell imaging Theileria Theileria parva Theileria parva - physiology
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