Outcome of hepatitis B e antigen-negative chronic hepatitis B on long-term nucleos(t)ide analog therapy starting with lamivudine

We determined the clinical outcome of hepatitis e antigen (HBeAg)-negative chronic hepatitis B patients treated with long-term nucleos(t)ide analog therapy starting with lamivudine. We evaluated 201 such patients treated for 3.8 +/- 1.4 years and 2 historical similar cohorts: 1 treated with interfer...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2005-07, Vol.42 (1), p.121-129
Hauptverfasser:	PAPATHEODORIDIS, George V, DIMOU, Evangelini, DIMAKOPOULOS, Konstantinos, MANOLAKOPOULOS, Spilios, RAPTI, Irene, KITIS, George, TZOURMAKLIOTIS, Dimitrios, MANESIS, Emanuel, HADZIYANNIS, Stephanos J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine - analogs & derivatives Adenine - therapeutic use Adolescent Adult Aged Antiviral Agents - therapeutic use Biological and medical sciences Carcinoma, Hepatocellular - etiology Female Fundamental and applied biological sciences. Psychology Hepatitis B e Antigens - immunology Hepatitis B, Chronic - complications Hepatitis B, Chronic - drug therapy Hepatitis B, Chronic - immunology Hepatitis B, Chronic - mortality Human viral diseases Humans Infectious diseases Interferon-alpha - therapeutic use Lamivudine - therapeutic use Liver Failure - etiology Liver Neoplasms - etiology Liver. Bile. Biliary tracts Male Medical sciences Middle Aged Nucleosides - agonists Nucleotides - agonists Organophosphonates - therapeutic use Retrospective Studies Survival Analysis Treatment Outcome Vertebrates: digestive system Viral diseases Viral diseases of the digestive system Viral hepatitis
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