Transcriptional Changes Underlying the Secretory Activation Phase of Mammary Gland Development

The secretory activation stage of mammary gland development occurs after parturition and converts inactive lobuloalveoli to active milk secretion. This process is triggered by progestin withdrawal and depends upon augmented prolactin (Prl) signaling. Little is known about the Prl-induced transcripti...

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Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2005-07, Vol.19 (7), p.1868-1883
Hauptverfasser:	Naylor, Matthew J, Oakes, Samantha R, Gardiner-Garden, Margaret, Harris, Jessica, Blazek, Katrina, Ho, Timothy W. C, Li, Foo C, Wynick, David, Walker, Ameae M, Ormandy, Christopher J
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Animals Cells, Cultured DNA-Binding Proteins - antagonists & inhibitors DNA-Binding Proteins - metabolism Female Galanin - genetics Gene Expression Profiling Lactation - genetics Lipids - biosynthesis Mammary Glands, Animal - anatomy & histology Mammary Glands, Animal - growth & development Mammary Glands, Animal - secretion Mice Mice, Knockout Milk Proteins - antagonists & inhibitors Milk Proteins - metabolism Mutation Oligonucleotide Array Sequence Analysis Phosphorylation Prolactin - genetics Prolactin - metabolism Prolactin - pharmacology Protein Biosynthesis - genetics STAT5 Transcription Factor Trans-Activators - antagonists & inhibitors Trans-Activators - metabolism Transcription, Genetic
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