The Bone Marrow Functionally Contributes to Liver Fibrosis

Background & Aims Bone marrow (BM) cells may transdifferentiate into or fuse with organ parenchymal cells. BM therapy shows promise in murine models of cirrhosis, and clinical trials of bone marrow stem cell therapy for organ healing are underway. However, the BM may contribute to scar-forming m...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2006-05, Vol.130 (6), p.1807-1821
Hauptverfasser:	Russo, Francesco P., Alison, Malcolm R., Bigger, Brian W., Amofah, Eunice, Florou, Aikaterini, Amin, Farhana, Bou–Gharios, George, Jeffery, Rosemary, Iredale, John P., Forbes, Stuart J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biopsy, Needle Bone Marrow Transplantation - adverse effects Bone Marrow Transplantation - methods Disease Models, Animal Disease Progression Female Immunohistochemistry Liver Cirrhosis - pathology Liver Cirrhosis - therapy Liver Regeneration - physiology Male Mice Mice, Inbred BALB C Photomicrography Sensitivity and Specificity Time Factors
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