Antisecretory Drugs for Diarrheal Disease

Acute diarrhea is a major cause of morbidity and mortality worldwide. Infants and pre-school children are the most vulnerable in whom there are 2–3 million deaths each year as a result of the associated dehydration and acidosis. Although oral rehydration therapy has reduced mortality during the past...

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Veröffentlicht in:	Digestive diseases (Basel) 2006-01, Vol.24 (1-2), p.47-58
1. Verfasser:	Farthing, Michael J.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidiarrheals - therapeutic use Chloride Channels - antagonists & inhibitors Chloride Channels - metabolism Diarrhea - drug therapy Enzyme Inhibitors - therapeutic use Humans Intestinal Mucosa - drug effects Intestinal Mucosa - secretion Neprilysin - adverse effects Receptors, Vasoactive Intestinal Peptide - antagonists & inhibitors Review Article Serotonin Antagonists - therapeutic use Substance P - antagonists & inhibitors Treatment Outcome
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