Can bioimpedance determine the volume of distribution of antibiotics in sepsis?

The relationship between the volume of distribution, assessed according to the two-compartmental pharmacokinetic model, and extracellular water estimated by bioimpedance was studied in mechanically ventilated patients with sepsis and capillary leak. A prospective observational study was performed in...

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Veröffentlicht in:	Anaesthesia and intensive care 2005-06, Vol.33 (3), p.345-350
Hauptverfasser:	BALIK, M, SEDIVY, J, WALDAUF, P, KOLAR, M, SMEJKALOVA, V, PACHL, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Bacterial Agents - pharmacokinetics Anti-Bacterial Agents - therapeutic use Biological and medical sciences Critical Care Drug Monitoring - methods Humans Medical sciences Metabolic Clearance Rate Middle Aged Netilmicin - pharmacokinetics Netilmicin - therapeutic use Sepsis - drug therapy Sepsis - metabolism Sepsis - mortality Vancomycin - pharmacokinetics Vancomycin - therapeutic use
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