X Chromosome Monosomy: A Common Mechanism for Autoimmune Diseases

The majority of human autoimmune diseases are characterized by female predominance. Although sex hormone influences have been suggested to explain this phenomenon, the mechanism remains unclear. In contrast to the role of hormones, it has been suggested, based on pilot data in primary biliary cirrho...

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Veröffentlicht in:	The Journal of immunology (1950) 2005-07, Vol.175 (1), p.575-578
Hauptverfasser:	Invernizzi, Pietro, Miozzo, Monica, Selmi, Carlo, Persani, Luca, Battezzati, Pier Maria, Zuin, Massimo, Lucchi, Simona, Meroni, Pier Luigi, Marasini, Bianca, Zeni, Silvana, Watnik, Mitchell, Grati, Francesca R, Simoni, Giuseppe, Gershwin, M. Eric, Podda, Mauro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Autoimmune Diseases - genetics B-Lymphocytes - ultrastructure Case-Control Studies Chimera - genetics Chromosomes, Human, X - genetics Chromosomes, Human, Y - genetics Female Graves Disease - genetics Humans In Situ Hybridization, Fluorescence In Vitro Techniques Middle Aged Monosomy Scleroderma, Systemic - genetics Sex Characteristics Sex Chromosome Aberrations T-Lymphocytes - ultrastructure Thyroiditis, Autoimmune - genetics
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