CD70 + antigen-presenting cells control the proliferation and differentiation of T cells in the intestinal mucosa

One unresolved issue in gut immunity is how mucosal T lymphocytes are activated and which antigen-presenting cell (APC) is critical for the regulation of this process. We have identified a unique population of APCs that is exclusively localized in the lamina propria. These APCs constitutively expres...

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Veröffentlicht in:	Nature immunology 2005-07, Vol.6 (7), p.698-706
Hauptverfasser:	Manjunath, N, Laouar, Amale, Haridas, Viraga, Vargas, Dorothy, Zhinan, Xia, Chaplin, David, van Lier, Rene A W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen Presentation - immunology Antigens, CD - immunology Biomedical and Life Sciences Biomedicine CD27 Ligand Cell Differentiation - immunology Flow Cytometry Immunohistochemistry Immunology Infectious Diseases Intestinal Mucosa - cytology Intestinal Mucosa - immunology Intestinal Mucosa - microbiology Listeria monocytogenes - immunology Listeriosis - immunology Listeriosis - pathology Lymphocyte Activation - immunology Lymphocytes Membrane Proteins - immunology Mice Mice, Inbred BALB C Mice, Inbred C57BL Mice, Knockout Mice, Transgenic Phagocytosis - immunology Specific Pathogen-Free Organisms T-Lymphocytes - cytology T-Lymphocytes - immunology Tumor Necrosis Factor Receptor Superfamily, Member 7 - immunology
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