Effect of cholesterol and ethanol on dermal delivery from DPPC liposomes

The main objective of the present work was to compare the dermal delivery of minoxidil (Mx), a lipophilic drug from ethosomes versus classic liposomes, containing different cholesterol (CHOL) concentrations. All the systems were characterized for shape, lamellarity, particle size and entrapment effi...

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Veröffentlicht in:	International journal of pharmaceutics 2005-07, Vol.298 (1), p.1-12
Hauptverfasser:	López-Pinto, J.M., González-Rodríguez, M.L., Rabasco, A.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Androstanes - administration & dosage Animals Biological and medical sciences Chemistry, Pharmaceutical Cholesterol - administration & dosage Confocal laser scanning microscopy Drug Stability Ethanol - administration & dosage Ethosome Franz cell General pharmacology Lamellarity Liposome Liposomes Medical sciences Minoxidil Minoxidil - administration & dosage Minoxidil - pharmacokinetics Particle Size Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Rats Rats, Wistar Skin Absorption
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