Influence of calcium on the proteolytic degradation of the calmodulin-like skin protein (calmodulin-like protein 5) in psoriatic epidermis

: The calmodulin‐like skin protein (CLSP) or so‐called calmodulin‐like protein 5, a recently discovered skin‐specific calcium‐binding protein, is closely related to keratinocyte differentiation. The 16‐kDa protein is proteolytically degraded in the upper layers of the stratum corneum (SC) of health...

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Veröffentlicht in:	Experimental dermatology 2006-06, Vol.15 (6), p.469-477
Hauptverfasser:	Méhul, Bruno, Bernard, Dominique, Brouard, Michel, Delattre, Caroline, Schmidt, Rainer
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Amino Acid Sequence Antibodies, Monoclonal - biosynthesis Biological and medical sciences Calcium - metabolism Calcium - pharmacology Calcium-Binding Proteins - genetics Calcium-Binding Proteins - immunology Calcium-Binding Proteins - metabolism Chelating Agents - pharmacology CLSP Dermatology epidermis Epidermis - drug effects Epidermis - metabolism Female Humans Immunohistochemistry In Vitro Techniques Male Medical sciences Middle Aged Peptide Hydrolases - metabolism proteolysis psoriasis Psoriasis - metabolism Psoriasis. Parapsoriasis. Lichen Recombinant Proteins - genetics Recombinant Proteins - immunology Recombinant Proteins - metabolism stratum corneum Transglutaminases - metabolism
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