The Predictive Value of Field versus Arrival Glasgow Coma Scale Score and TRISS Calculations in Moderate-to-Severe Traumatic Brain Injury
BACKGROUND:Glasgow Coma Scale (GCS) scores are widely used to quantify level of consciousness in the prehospital environment. The predictive value of field versus arrival GCS is not well defined but has tremendous implications with regard to triage and therapeutic decisions as well as the use of var...
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Veröffentlicht in: | The Journal of trauma, injury, infection, and critical care injury, infection, and critical care, 2006-05, Vol.60 (5), p.985-990 |
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description | BACKGROUND:Glasgow Coma Scale (GCS) scores are widely used to quantify level of consciousness in the prehospital environment. The predictive value of field versus arrival GCS is not well defined but has tremendous implications with regard to triage and therapeutic decisions as well as the use of various predictive scoring systems, such as Trauma Score and Injury Severity Score (TRISS). This study explores the predictive value of field GCS (fGCS) and arrival GCS (aGCS) as well as TRISS calculations using field (fTRISS) and arrival (aTRISS) data in patients with moderate-to-severe traumatic brain injury (TBI).
METHODS:Major trauma victims with head Abbreviated Injury Scores of 3 or greater were identified from our county trauma registry over a 16-year period. The predictive ability of fGCS with regard to aGCS was explored using univariate statistics and linear regression modeling. The difference between aGCS and fGCS was also modeled against mortality and the composite endpoint using logistic regression, adjusting for fGCS. The predictive value of preadmission GCS (pGCS), defined as either fGCS or aGCS in nonintubated patients without a documented fGCS, with regard to mortality and a composite endpoint representing the need for neurosurgical care (death, craniotomy, invasive intracranial pressure monitoring, or intensive care unit care >48 hours) was determined using receiver-operator curve (ROC) analysis. Finally, fTRISS and aTRISS predicted survival values were compared with each other and to observed survival.
RESULTS:A total of 12,882 patients were included. Mean values for fGCS and aGCS were similar (11.4 and 11.5, respectively, p = 0.336), and a strong correlation (r = 0.67, 95% CI 0.66–0.69, p < 0.0001) was observed between them. The difference between fGCS and aGCS was also predictive of outcome after adjusting for fGCS. Good predictive ability was observed for pGCS with regard to both mortality and neurosurgical intervention. Both fTRISS and aTRISS predicted survival values were nearly identical to observed survival. Observed and fTRISS predicted survival were nearly identical in patients undergoing prehospital intubation
CONCLUSIONS:Values for fGCS are highly predictive of aGCS, and both are associated with outcome from TBI. A change in GCS from the field to arrival is highly predictive of outcome. The use of field data for TRISS calculations appears to be a valid methodological approach, even in severely injured TBI patients undergoing prehospital |
doi_str_mv | 10.1097/01.ta.0000205860.96209.1c |
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METHODS:Major trauma victims with head Abbreviated Injury Scores of 3 or greater were identified from our county trauma registry over a 16-year period. The predictive ability of fGCS with regard to aGCS was explored using univariate statistics and linear regression modeling. The difference between aGCS and fGCS was also modeled against mortality and the composite endpoint using logistic regression, adjusting for fGCS. The predictive value of preadmission GCS (pGCS), defined as either fGCS or aGCS in nonintubated patients without a documented fGCS, with regard to mortality and a composite endpoint representing the need for neurosurgical care (death, craniotomy, invasive intracranial pressure monitoring, or intensive care unit care >48 hours) was determined using receiver-operator curve (ROC) analysis. Finally, fTRISS and aTRISS predicted survival values were compared with each other and to observed survival.
RESULTS:A total of 12,882 patients were included. Mean values for fGCS and aGCS were similar (11.4 and 11.5, respectively, p = 0.336), and a strong correlation (r = 0.67, 95% CI 0.66–0.69, p < 0.0001) was observed between them. The difference between fGCS and aGCS was also predictive of outcome after adjusting for fGCS. Good predictive ability was observed for pGCS with regard to both mortality and neurosurgical intervention. Both fTRISS and aTRISS predicted survival values were nearly identical to observed survival. Observed and fTRISS predicted survival were nearly identical in patients undergoing prehospital intubation
CONCLUSIONS:Values for fGCS are highly predictive of aGCS, and both are associated with outcome from TBI. A change in GCS from the field to arrival is highly predictive of outcome. The use of field data for TRISS calculations appears to be a valid methodological approach, even in severely injured TBI patients undergoing prehospital intubation.</description><identifier>ISSN: 0022-5282</identifier><identifier>EISSN: 1529-8809</identifier><identifier>DOI: 10.1097/01.ta.0000205860.96209.1c</identifier><identifier>PMID: 16688059</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Biological and medical sciences ; Brain Injuries - classification ; Brain Injuries - diagnosis ; Brain Injuries - mortality ; Brain Injuries - surgery ; California ; Diseases of the osteoarticular system ; Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes ; Emergency Medical Services ; Emergency Medical Technicians ; Emergency Service, Hospital ; Glasgow Coma Scale ; Hospital Mortality ; Humans ; Injuries of the nervous system and the skull. Diseases due to physical agents ; Injury Severity Score ; Medical sciences ; Nervous system (semeiology, syndromes) ; Neurology ; Prognosis ; Registries ; Regression Analysis ; Reproducibility of Results ; Retrospective Studies ; ROC Curve ; Statistics as Topic ; Survival Analysis ; Trauma Severity Indices ; Traumas. Diseases due to physical agents ; Unconsciousness - classification ; Unconsciousness - diagnosis ; Unconsciousness - mortality</subject><ispartof>The Journal of trauma, injury, infection, and critical care, 2006-05, Vol.60 (5), p.985-990</ispartof><rights>2006 Lippincott Williams & Wilkins, Inc.</rights><rights>2006 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4569-d4fd3b94030bf8d98060e06a10293e4cc606d1e5510ae43e238f5d55eddeb8373</citedby><cites>FETCH-LOGICAL-c4569-d4fd3b94030bf8d98060e06a10293e4cc606d1e5510ae43e238f5d55eddeb8373</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17795028$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16688059$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Davis, Daniel P.</creatorcontrib><creatorcontrib>Serrano, Jennifer A.</creatorcontrib><creatorcontrib>Vilke, Gary M.</creatorcontrib><creatorcontrib>Sise, Michael J.</creatorcontrib><creatorcontrib>Kennedy, Frank</creatorcontrib><creatorcontrib>Eastman, A Brent</creatorcontrib><creatorcontrib>Velky, Thomas</creatorcontrib><creatorcontrib>Hoyt, David B.</creatorcontrib><title>The Predictive Value of Field versus Arrival Glasgow Coma Scale Score and TRISS Calculations in Moderate-to-Severe Traumatic Brain Injury</title><title>The Journal of trauma, injury, infection, and critical care</title><addtitle>J Trauma</addtitle><description>BACKGROUND:Glasgow Coma Scale (GCS) scores are widely used to quantify level of consciousness in the prehospital environment. The predictive value of field versus arrival GCS is not well defined but has tremendous implications with regard to triage and therapeutic decisions as well as the use of various predictive scoring systems, such as Trauma Score and Injury Severity Score (TRISS). This study explores the predictive value of field GCS (fGCS) and arrival GCS (aGCS) as well as TRISS calculations using field (fTRISS) and arrival (aTRISS) data in patients with moderate-to-severe traumatic brain injury (TBI).
METHODS:Major trauma victims with head Abbreviated Injury Scores of 3 or greater were identified from our county trauma registry over a 16-year period. The predictive ability of fGCS with regard to aGCS was explored using univariate statistics and linear regression modeling. The difference between aGCS and fGCS was also modeled against mortality and the composite endpoint using logistic regression, adjusting for fGCS. The predictive value of preadmission GCS (pGCS), defined as either fGCS or aGCS in nonintubated patients without a documented fGCS, with regard to mortality and a composite endpoint representing the need for neurosurgical care (death, craniotomy, invasive intracranial pressure monitoring, or intensive care unit care >48 hours) was determined using receiver-operator curve (ROC) analysis. Finally, fTRISS and aTRISS predicted survival values were compared with each other and to observed survival.
RESULTS:A total of 12,882 patients were included. Mean values for fGCS and aGCS were similar (11.4 and 11.5, respectively, p = 0.336), and a strong correlation (r = 0.67, 95% CI 0.66–0.69, p < 0.0001) was observed between them. The difference between fGCS and aGCS was also predictive of outcome after adjusting for fGCS. Good predictive ability was observed for pGCS with regard to both mortality and neurosurgical intervention. Both fTRISS and aTRISS predicted survival values were nearly identical to observed survival. Observed and fTRISS predicted survival were nearly identical in patients undergoing prehospital intubation
CONCLUSIONS:Values for fGCS are highly predictive of aGCS, and both are associated with outcome from TBI. A change in GCS from the field to arrival is highly predictive of outcome. The use of field data for TRISS calculations appears to be a valid methodological approach, even in severely injured TBI patients undergoing prehospital intubation.</description><subject>Biological and medical sciences</subject><subject>Brain Injuries - classification</subject><subject>Brain Injuries - diagnosis</subject><subject>Brain Injuries - mortality</subject><subject>Brain Injuries - surgery</subject><subject>California</subject><subject>Diseases of the osteoarticular system</subject><subject>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</subject><subject>Emergency Medical Services</subject><subject>Emergency Medical Technicians</subject><subject>Emergency Service, Hospital</subject><subject>Glasgow Coma Scale</subject><subject>Hospital Mortality</subject><subject>Humans</subject><subject>Injuries of the nervous system and the skull. Diseases due to physical agents</subject><subject>Injury Severity Score</subject><subject>Medical sciences</subject><subject>Nervous system (semeiology, syndromes)</subject><subject>Neurology</subject><subject>Prognosis</subject><subject>Registries</subject><subject>Regression Analysis</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>ROC Curve</subject><subject>Statistics as Topic</subject><subject>Survival Analysis</subject><subject>Trauma Severity Indices</subject><subject>Traumas. Diseases due to physical agents</subject><subject>Unconsciousness - classification</subject><subject>Unconsciousness - diagnosis</subject><subject>Unconsciousness - mortality</subject><issn>0022-5282</issn><issn>1529-8809</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkd9u0zAUxiMEYmXwCshcwF3CcRIn9uWo2Kg0BKKFW-vUPqEZTjzspNUegbfGWyvVF7aO_Tt__H1Z9o5DwUG1H4EXExaQVglCNlCopgRVcPMsW3BRqlxKUM-zRXovc1HK8iJ7FeNd4uu6ki-zC940CRFqkf3b7Ih9D2R7M_V7Yr_QzcR8x657cpbtKcQ5sqsQ-j06duMw_vYHtvQDsrVBR2n3gRiOlm1-rNZrtkRnZodT78fI-pF99ZYCTpRPPl9TqkdsE3AeEmHYp4AJWY13c3h4nb3o0EV6czovs5_XnzfLL_ntt5vV8uo2N7VoVG7rzlZbVUMF205aJaEBggY5lKqi2pgGGstJCA5IdUVlJTthhSBraSurtrrMPhzr3gf_d6Y46aGPhpzDkfwcddMq0QIXCVRH0AQfY6BO34d-wPCgOehHHzRwPaE--6CffNDcpNy3pybzdiB7zjwJn4D3JwBj0rELOJo-nrk2TQGlTFx95A7eTcmMP24-UNA7QjftnlqL9Ke8hCSDSFH-eKWq_xGcoZA</recordid><startdate>200605</startdate><enddate>200605</enddate><creator>Davis, Daniel P.</creator><creator>Serrano, Jennifer A.</creator><creator>Vilke, Gary M.</creator><creator>Sise, Michael J.</creator><creator>Kennedy, Frank</creator><creator>Eastman, A Brent</creator><creator>Velky, Thomas</creator><creator>Hoyt, David B.</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200605</creationdate><title>The Predictive Value of Field versus Arrival Glasgow Coma Scale Score and TRISS Calculations in Moderate-to-Severe Traumatic Brain Injury</title><author>Davis, Daniel P. ; Serrano, Jennifer A. ; Vilke, Gary M. ; Sise, Michael J. ; Kennedy, Frank ; Eastman, A Brent ; Velky, Thomas ; Hoyt, David B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4569-d4fd3b94030bf8d98060e06a10293e4cc606d1e5510ae43e238f5d55eddeb8373</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Biological and medical sciences</topic><topic>Brain Injuries - classification</topic><topic>Brain Injuries - diagnosis</topic><topic>Brain Injuries - mortality</topic><topic>Brain Injuries - surgery</topic><topic>California</topic><topic>Diseases of the osteoarticular system</topic><topic>Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes</topic><topic>Emergency Medical Services</topic><topic>Emergency Medical Technicians</topic><topic>Emergency Service, Hospital</topic><topic>Glasgow Coma Scale</topic><topic>Hospital Mortality</topic><topic>Humans</topic><topic>Injuries of the nervous system and the skull. Diseases due to physical agents</topic><topic>Injury Severity Score</topic><topic>Medical sciences</topic><topic>Nervous system (semeiology, syndromes)</topic><topic>Neurology</topic><topic>Prognosis</topic><topic>Registries</topic><topic>Regression Analysis</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><topic>ROC Curve</topic><topic>Statistics as Topic</topic><topic>Survival Analysis</topic><topic>Trauma Severity Indices</topic><topic>Traumas. Diseases due to physical agents</topic><topic>Unconsciousness - classification</topic><topic>Unconsciousness - diagnosis</topic><topic>Unconsciousness - mortality</topic><toplevel>online_resources</toplevel><creatorcontrib>Davis, Daniel P.</creatorcontrib><creatorcontrib>Serrano, Jennifer A.</creatorcontrib><creatorcontrib>Vilke, Gary M.</creatorcontrib><creatorcontrib>Sise, Michael J.</creatorcontrib><creatorcontrib>Kennedy, Frank</creatorcontrib><creatorcontrib>Eastman, A Brent</creatorcontrib><creatorcontrib>Velky, Thomas</creatorcontrib><creatorcontrib>Hoyt, David B.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of trauma, injury, infection, and critical care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Davis, Daniel P.</au><au>Serrano, Jennifer A.</au><au>Vilke, Gary M.</au><au>Sise, Michael J.</au><au>Kennedy, Frank</au><au>Eastman, A Brent</au><au>Velky, Thomas</au><au>Hoyt, David B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Predictive Value of Field versus Arrival Glasgow Coma Scale Score and TRISS Calculations in Moderate-to-Severe Traumatic Brain Injury</atitle><jtitle>The Journal of trauma, injury, infection, and critical care</jtitle><addtitle>J Trauma</addtitle><date>2006-05</date><risdate>2006</risdate><volume>60</volume><issue>5</issue><spage>985</spage><epage>990</epage><pages>985-990</pages><issn>0022-5282</issn><eissn>1529-8809</eissn><abstract>BACKGROUND:Glasgow Coma Scale (GCS) scores are widely used to quantify level of consciousness in the prehospital environment. The predictive value of field versus arrival GCS is not well defined but has tremendous implications with regard to triage and therapeutic decisions as well as the use of various predictive scoring systems, such as Trauma Score and Injury Severity Score (TRISS). This study explores the predictive value of field GCS (fGCS) and arrival GCS (aGCS) as well as TRISS calculations using field (fTRISS) and arrival (aTRISS) data in patients with moderate-to-severe traumatic brain injury (TBI).
METHODS:Major trauma victims with head Abbreviated Injury Scores of 3 or greater were identified from our county trauma registry over a 16-year period. The predictive ability of fGCS with regard to aGCS was explored using univariate statistics and linear regression modeling. The difference between aGCS and fGCS was also modeled against mortality and the composite endpoint using logistic regression, adjusting for fGCS. The predictive value of preadmission GCS (pGCS), defined as either fGCS or aGCS in nonintubated patients without a documented fGCS, with regard to mortality and a composite endpoint representing the need for neurosurgical care (death, craniotomy, invasive intracranial pressure monitoring, or intensive care unit care >48 hours) was determined using receiver-operator curve (ROC) analysis. Finally, fTRISS and aTRISS predicted survival values were compared with each other and to observed survival.
RESULTS:A total of 12,882 patients were included. Mean values for fGCS and aGCS were similar (11.4 and 11.5, respectively, p = 0.336), and a strong correlation (r = 0.67, 95% CI 0.66–0.69, p < 0.0001) was observed between them. The difference between fGCS and aGCS was also predictive of outcome after adjusting for fGCS. Good predictive ability was observed for pGCS with regard to both mortality and neurosurgical intervention. Both fTRISS and aTRISS predicted survival values were nearly identical to observed survival. Observed and fTRISS predicted survival were nearly identical in patients undergoing prehospital intubation
CONCLUSIONS:Values for fGCS are highly predictive of aGCS, and both are associated with outcome from TBI. A change in GCS from the field to arrival is highly predictive of outcome. The use of field data for TRISS calculations appears to be a valid methodological approach, even in severely injured TBI patients undergoing prehospital intubation.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>16688059</pmid><doi>10.1097/01.ta.0000205860.96209.1c</doi><tpages>6</tpages></addata></record> |
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subjects | Biological and medical sciences Brain Injuries - classification Brain Injuries - diagnosis Brain Injuries - mortality Brain Injuries - surgery California Diseases of the osteoarticular system Disorders of higher nervous function. Focal brain diseases. Central vestibular syndrome and deafness. Brain stem syndromes Emergency Medical Services Emergency Medical Technicians Emergency Service, Hospital Glasgow Coma Scale Hospital Mortality Humans Injuries of the nervous system and the skull. Diseases due to physical agents Injury Severity Score Medical sciences Nervous system (semeiology, syndromes) Neurology Prognosis Registries Regression Analysis Reproducibility of Results Retrospective Studies ROC Curve Statistics as Topic Survival Analysis Trauma Severity Indices Traumas. Diseases due to physical agents Unconsciousness - classification Unconsciousness - diagnosis Unconsciousness - mortality |
title | The Predictive Value of Field versus Arrival Glasgow Coma Scale Score and TRISS Calculations in Moderate-to-Severe Traumatic Brain Injury |
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