Yin yang 1 (YY1) represses histidine decarboxylase gene expression with SREBP-1a in part through an upstream Sp1 site

Histidine decarboxylase (HDC) is the enzyme that converts histidine to histamine, a bioamine that plays an important role in many physiological aspects including allergic responses, inflammation, neurotransmission, and gastric acid secretion. In previous studies, we demonstrated that Kruppel-like fa...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2006-06, Vol.290 (6), p.G1096-G1104
Hauptverfasser:	Ai, Wandong, Liu, Ying, Wang, Timothy C
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Cell Line Enzyme Repression - physiology Epithelial Cells - metabolism Gastrins - metabolism Gene Expression Regulation - physiology Histidine Decarboxylase - genetics Histidine Decarboxylase - metabolism Protein Binding Recombinant Proteins - metabolism Sp1 Transcription Factor - genetics Sp1 Transcription Factor - metabolism Sterol Regulatory Element Binding Protein 1 - genetics Sterol Regulatory Element Binding Protein 1 - metabolism Stomach - metabolism YY1 Transcription Factor - genetics YY1 Transcription Factor - metabolism
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