Molecular biomarkers for the study of childhood leukemia

Various specific chromosome rearrangements, including t(8;21), t(15;17), and inv(16), are found in acute myeloid leukemia (AML) and in childhood acute lymphocytic leukemia (ALL), t(12;21) and t(1;19) are common. We sequenced the translocation breakpoints of 56 patients with childhood ALL or AML harb...

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Veröffentlicht in:	Toxicology and applied pharmacology 2005-08, Vol.206 (2), p.237-245
Hauptverfasser:	Smith, Martyn T., McHale, Cliona M., Wiemels, Joseph L., Zhang, Luoping, Wiencke, John K., Zheng, Shichun, Gunn, Laura, Skibola, Christine F., Ma, Xiaomei, Buffler, Patricia A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Child Children Chromosome translocations Cytogenetics DNA Methylation Folic Acid - metabolism Gene Expression Profiling Humans Leukemia Leukemia, Myeloid, Acute - etiology Leukemia, Myeloid, Acute - genetics Molecular epidemiology NAD(P)H Dehydrogenase (Quinone) - genetics Neonatal blood spots Pesticides Precursor Cell Lymphoblastic Leukemia-Lymphoma - etiology Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics Proteomics Risk Factors Translocation, Genetic
Online-Zugang:	Volltext
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