Identification of an Intracellular Trafficking and Assembly Pathway for HIV‐1 Gag

Retroviral Gag proteins are membrane‐bound polyproteins that are necessary and sufficient for virus‐like particle (VLP) formation. It is not known how Gag traffics through the cell or how the site of particle production is determined. Here we use two techniques, biarsenical/tetracysteine (TC) labeli...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2006-06, Vol.7 (6), p.731-745
Hauptverfasser:	Perlman, Mira, Resh, Marilyn D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arsenicals Base Sequence Calcium Signaling Cercopithecus aethiops COS Cells Cycloheximide - pharmacology DNA, Viral - genetics Fluorescent Dyes Gag Gene Products, gag - genetics Gene Products, gag - metabolism HeLa Cells HIV-1 - drug effects HIV-1 - genetics HIV-1 - metabolism HIV-1 - physiology HIV‐1 Human immunodeficiency virus 1 Humans In Vitro Techniques membranes Microscopy, Electron multivesicular body/exocytosis Protein Synthesis Inhibitors - pharmacology Protein Transport - drug effects Transfection viral particle assembly Virus Assembly
Online-Zugang:	Volltext
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