Activation of STAT3 is a marker of poor prognosis in human colorectal cancer

It is known that the signal transducer and activator of transcription 3 (STAT3) is a key signaling molecule implicated in the regulation of growth and malignant transformation. Constitutive activation of STAT3 has been observed in a number of tumour-derived cell lines, as well as in a wide variety o...

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Veröffentlicht in:	Oncology reports 2006-06, Vol.15 (6), p.1445-1451
Hauptverfasser:	KUSABA, Takafumi, NAKAYAMA, Toshiyuki, YAMAZUMI, Kazuyuki, YAKATA, Yuichi, YOSHIZAKI, Ayumi, INOUE, Kenichiro, NAGAYASU, Takeshi, SEKINE, Ichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - metabolism Adenocarcinoma - pathology Adult Aged Aged, 80 and over Biological and medical sciences Colorectal Neoplasms - metabolism Colorectal Neoplasms - pathology Disease-Free Survival Female Gastroenterology. Liver. Pancreas. Abdomen Humans Lymphatic Metastasis Male Medical sciences Middle Aged Neoplasm Staging STAT3 Transcription Factor - biosynthesis STAT3 Transcription Factor - metabolism Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
Online-Zugang:	Volltext
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