Retroperitoneoscopic Donor Nephrectomy: A Retrospective, Non-Randomized Comparison of Early Complications, Donor and Recipient Outcome with the Standard Open Approach
We retrospectively performed a comparative analysis of retroperitoneoscopic and open donor nephrectomy in terms of donor complications, as well as recipient complications and functional graft outcome. A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephre...
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Veröffentlicht in: | European urology 2005-07, Vol.48 (1), p.90-96 |
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creator | Bachmann, Alexander Wolff, Thomas Ruszat, Robin Giannini, Olivier Dickenmann, Michael Gürke, Lorenz Steiger, Jürg Gasser, Thomas C. Stief, Christian G. Sulser, Tullio |
description | We retrospectively performed a comparative analysis of retroperitoneoscopic and open donor nephrectomy in terms of donor complications, as well as recipient complications and functional graft outcome.
A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephrectomies was analyzed retrospectively. Both groups were comparable in terms of age, body mass index (BMI), operating time (OPT), warm ischemia time (WIT) and blood loss.
There were no statistically significant differences with respect to recipient outcome, mean values for age, BMI, OPT and cold ischemia time (CIT). The overall donor complication rate did not differ. Early functional graft follow-up showed significant differences in 24
h-urine output between the two groups (
p
<
0.001), but serum creatinine was comparable after 7, 30, 180 and 365 days. The early rejection rate in the recipients was similar in the two groups.
Retroperitoneoscopic donor nephrectomy (RDN) provides comparable perioperative features, such as operating time, warm ischemia time (WIT) and overall complication rate to the open donor nephrectomy (ODN). Additionally, it has no negative impact on recipients’ operating time, graft ischemia and early graft function. |
doi_str_mv | 10.1016/j.eururo.2005.03.007 |
format | Article |
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A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephrectomies was analyzed retrospectively. Both groups were comparable in terms of age, body mass index (BMI), operating time (OPT), warm ischemia time (WIT) and blood loss.
There were no statistically significant differences with respect to recipient outcome, mean values for age, BMI, OPT and cold ischemia time (CIT). The overall donor complication rate did not differ. Early functional graft follow-up showed significant differences in 24
h-urine output between the two groups (
p
<
0.001), but serum creatinine was comparable after 7, 30, 180 and 365 days. The early rejection rate in the recipients was similar in the two groups.
Retroperitoneoscopic donor nephrectomy (RDN) provides comparable perioperative features, such as operating time, warm ischemia time (WIT) and overall complication rate to the open donor nephrectomy (ODN). Additionally, it has no negative impact on recipients’ operating time, graft ischemia and early graft function.</description><identifier>ISSN: 0302-2838</identifier><identifier>EISSN: 1873-7560</identifier><identifier>DOI: 10.1016/j.eururo.2005.03.007</identifier><identifier>PMID: 15967257</identifier><language>eng</language><publisher>Switzerland: Elsevier B.V</publisher><subject>Adult ; Aged ; Comparison of techniques ; Donor nephrectomy ; Female ; Follow-Up Studies ; Graft Rejection ; Humans ; Intraoperative Complications ; Kidney Transplantation - adverse effects ; Kidney Transplantation - methods ; Laparoscopy ; Living Donors ; Male ; Middle Aged ; Nephrectomy - adverse effects ; Nephrectomy - methods ; Postoperative Complications ; Recipient outcome ; Retroperitoneoscopy ; Retrospective Studies ; Time Factors</subject><ispartof>European urology, 2005-07, Vol.48 (1), p.90-96</ispartof><rights>2005 Elsevier B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c360t-496da4e27fb0df5bf012eadf08c1389e03765d423dbce28fd3828ff40906142f3</citedby><cites>FETCH-LOGICAL-c360t-496da4e27fb0df5bf012eadf08c1389e03765d423dbce28fd3828ff40906142f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0302283805001417$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27903,27904,65309</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15967257$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bachmann, Alexander</creatorcontrib><creatorcontrib>Wolff, Thomas</creatorcontrib><creatorcontrib>Ruszat, Robin</creatorcontrib><creatorcontrib>Giannini, Olivier</creatorcontrib><creatorcontrib>Dickenmann, Michael</creatorcontrib><creatorcontrib>Gürke, Lorenz</creatorcontrib><creatorcontrib>Steiger, Jürg</creatorcontrib><creatorcontrib>Gasser, Thomas C.</creatorcontrib><creatorcontrib>Stief, Christian G.</creatorcontrib><creatorcontrib>Sulser, Tullio</creatorcontrib><title>Retroperitoneoscopic Donor Nephrectomy: A Retrospective, Non-Randomized Comparison of Early Complications, Donor and Recipient Outcome with the Standard Open Approach</title><title>European urology</title><addtitle>Eur Urol</addtitle><description>We retrospectively performed a comparative analysis of retroperitoneoscopic and open donor nephrectomy in terms of donor complications, as well as recipient complications and functional graft outcome.
A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephrectomies was analyzed retrospectively. Both groups were comparable in terms of age, body mass index (BMI), operating time (OPT), warm ischemia time (WIT) and blood loss.
There were no statistically significant differences with respect to recipient outcome, mean values for age, BMI, OPT and cold ischemia time (CIT). The overall donor complication rate did not differ. Early functional graft follow-up showed significant differences in 24
h-urine output between the two groups (
p
<
0.001), but serum creatinine was comparable after 7, 30, 180 and 365 days. The early rejection rate in the recipients was similar in the two groups.
Retroperitoneoscopic donor nephrectomy (RDN) provides comparable perioperative features, such as operating time, warm ischemia time (WIT) and overall complication rate to the open donor nephrectomy (ODN). Additionally, it has no negative impact on recipients’ operating time, graft ischemia and early graft function.</description><subject>Adult</subject><subject>Aged</subject><subject>Comparison of techniques</subject><subject>Donor nephrectomy</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Graft Rejection</subject><subject>Humans</subject><subject>Intraoperative Complications</subject><subject>Kidney Transplantation - adverse effects</subject><subject>Kidney Transplantation - methods</subject><subject>Laparoscopy</subject><subject>Living Donors</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nephrectomy - adverse effects</subject><subject>Nephrectomy - methods</subject><subject>Postoperative Complications</subject><subject>Recipient outcome</subject><subject>Retroperitoneoscopy</subject><subject>Retrospective Studies</subject><subject>Time Factors</subject><issn>0302-2838</issn><issn>1873-7560</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kc1qGzEUhUVpaFy3b1CKVl1lJndG89tFwbjpD4QY0nYtZOkKy8yMVEmT4jxQnrNybOiuGwku55zLPR8h7wrICyia632Os5-9zUuAOgeWA7QvyKLoWpa1dQMvyQIYlFnZse6SvA5hDwCs7tkrclnUfdOWdbsgT_cYvXXoTbQT2iCtM5J-tpP19A7dzqOMdjx8pCv6rAwuDcwDXtE7O2X3YlJ2NI-o6NqOTngT7EStpjfCD4fn2WCkiMZO4eqcmiwpShpncIp0M0dpR6R_TNzRuEP6IyaB8IpuHE505Zy3Qu7ekAsthoBvz_-S_Ppy83P9LbvdfP2-Xt1mkjUQs6pvlKiwbPUWlK63GooShdLQyYJ1PQJrm1pVJVNbiWWnFevSqyvooSmqUrMl-XDKTWt_zxgiH02QOAwilTMH3rR9zdrU45JUJ6FMnQSPmjtvRuEPvAB-5MP3_MSHH_lwYDzxSbb35_x5O6L6ZzoDSYJPJwGmKx8Meh5kKkqiMkcUXFnz_w1_AWNcp4U</recordid><startdate>20050701</startdate><enddate>20050701</enddate><creator>Bachmann, Alexander</creator><creator>Wolff, Thomas</creator><creator>Ruszat, Robin</creator><creator>Giannini, Olivier</creator><creator>Dickenmann, Michael</creator><creator>Gürke, Lorenz</creator><creator>Steiger, Jürg</creator><creator>Gasser, Thomas C.</creator><creator>Stief, Christian G.</creator><creator>Sulser, Tullio</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050701</creationdate><title>Retroperitoneoscopic Donor Nephrectomy: A Retrospective, Non-Randomized Comparison of Early Complications, Donor and Recipient Outcome with the Standard Open Approach</title><author>Bachmann, Alexander ; Wolff, Thomas ; Ruszat, Robin ; Giannini, Olivier ; Dickenmann, Michael ; Gürke, Lorenz ; Steiger, Jürg ; Gasser, Thomas C. ; Stief, Christian G. ; Sulser, Tullio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c360t-496da4e27fb0df5bf012eadf08c1389e03765d423dbce28fd3828ff40906142f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Comparison of techniques</topic><topic>Donor nephrectomy</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Graft Rejection</topic><topic>Humans</topic><topic>Intraoperative Complications</topic><topic>Kidney Transplantation - adverse effects</topic><topic>Kidney Transplantation - methods</topic><topic>Laparoscopy</topic><topic>Living Donors</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nephrectomy - adverse effects</topic><topic>Nephrectomy - methods</topic><topic>Postoperative Complications</topic><topic>Recipient outcome</topic><topic>Retroperitoneoscopy</topic><topic>Retrospective Studies</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bachmann, Alexander</creatorcontrib><creatorcontrib>Wolff, Thomas</creatorcontrib><creatorcontrib>Ruszat, Robin</creatorcontrib><creatorcontrib>Giannini, Olivier</creatorcontrib><creatorcontrib>Dickenmann, Michael</creatorcontrib><creatorcontrib>Gürke, Lorenz</creatorcontrib><creatorcontrib>Steiger, Jürg</creatorcontrib><creatorcontrib>Gasser, Thomas C.</creatorcontrib><creatorcontrib>Stief, Christian G.</creatorcontrib><creatorcontrib>Sulser, Tullio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European urology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bachmann, Alexander</au><au>Wolff, Thomas</au><au>Ruszat, Robin</au><au>Giannini, Olivier</au><au>Dickenmann, Michael</au><au>Gürke, Lorenz</au><au>Steiger, Jürg</au><au>Gasser, Thomas C.</au><au>Stief, Christian G.</au><au>Sulser, Tullio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Retroperitoneoscopic Donor Nephrectomy: A Retrospective, Non-Randomized Comparison of Early Complications, Donor and Recipient Outcome with the Standard Open Approach</atitle><jtitle>European urology</jtitle><addtitle>Eur Urol</addtitle><date>2005-07-01</date><risdate>2005</risdate><volume>48</volume><issue>1</issue><spage>90</spage><epage>96</epage><pages>90-96</pages><issn>0302-2838</issn><eissn>1873-7560</eissn><abstract>We retrospectively performed a comparative analysis of retroperitoneoscopic and open donor nephrectomy in terms of donor complications, as well as recipient complications and functional graft outcome.
A total of 134 donor nephrectomies including 69 open (ODN) and 65 retroperitoneoscopic (RDN) nephrectomies was analyzed retrospectively. Both groups were comparable in terms of age, body mass index (BMI), operating time (OPT), warm ischemia time (WIT) and blood loss.
There were no statistically significant differences with respect to recipient outcome, mean values for age, BMI, OPT and cold ischemia time (CIT). The overall donor complication rate did not differ. Early functional graft follow-up showed significant differences in 24
h-urine output between the two groups (
p
<
0.001), but serum creatinine was comparable after 7, 30, 180 and 365 days. The early rejection rate in the recipients was similar in the two groups.
Retroperitoneoscopic donor nephrectomy (RDN) provides comparable perioperative features, such as operating time, warm ischemia time (WIT) and overall complication rate to the open donor nephrectomy (ODN). Additionally, it has no negative impact on recipients’ operating time, graft ischemia and early graft function.</abstract><cop>Switzerland</cop><pub>Elsevier B.V</pub><pmid>15967257</pmid><doi>10.1016/j.eururo.2005.03.007</doi><tpages>7</tpages></addata></record> |
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subjects | Adult Aged Comparison of techniques Donor nephrectomy Female Follow-Up Studies Graft Rejection Humans Intraoperative Complications Kidney Transplantation - adverse effects Kidney Transplantation - methods Laparoscopy Living Donors Male Middle Aged Nephrectomy - adverse effects Nephrectomy - methods Postoperative Complications Recipient outcome Retroperitoneoscopy Retrospective Studies Time Factors |
title | Retroperitoneoscopic Donor Nephrectomy: A Retrospective, Non-Randomized Comparison of Early Complications, Donor and Recipient Outcome with the Standard Open Approach |
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