Failure of a killed Leishmania amazonensis vaccine against American cutaneous leishmaniasis in Colombia

We report the results of a double-blind, randomized, placebo-controlled clinical trial of a killed whole-cell Leishmania amazonensis candidate vaccine against American cutaneous leishmaniasis (CL) in Colombia. The trial subjects were 2597 healthy volunteers with negative leishmanin skin test (LST) s...

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Veröffentlicht in:	Transactions of the Royal Society of Tropical Medicine and Hygiene 2005-08, Vol.99 (8), p.593-598
Hauptverfasser:	Vélez, Iván D., Gilchrist, Katherine, Arbelaez, María P., Rojas, Carlos A., Puerta, Juan A., Antunes, Carlos M.F., Zicker, Fabio, Modabber, Farrokh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Animals Biological and medical sciences Colombia Colombia - epidemiology Cutaneous leishmaniasis Double-Blind Method General aspects Humans Incidence Leishmania - immunology Leishmania amazonensis Leishmaniasis, Cutaneous - epidemiology Leishmaniasis, Cutaneous - prevention & control Leishvacin Male Medical sciences Military Personnel Protozoan Vaccines - therapeutic use Rural Health Survival Analysis Treatment Failure Vaccines, Inactivated - therapeutic use
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