2,6-Diisopropylphenol Protects Osteoblasts from Oxidative Stress-Induced Apoptosis through Suppression of Caspase-3 Activation

: 2,6‐Diisopropylphenol is an intravenous anesthetic agent used for induction and maintenance of anesthesia. Since it is similar to α‐tocopherol, 2,6‐diisopropylphenol may have antioxidant effects. Osteoblasts play important roles in bone remodeling. In this study, we attempted to evaluate the prote...

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Veröffentlicht in:	Annals of the New York Academy of Sciences 2005-05, Vol.1042 (1), p.448-459
Hauptverfasser:	CHEN, RUEI-MING, WU, GONG-JHE, CHANG, HWA-CHIA, CHEN, JUE-TAI, CHEN, TZENG-FU, LIN, YI-LING, CHEN, TA-LIANG
Format:	Artikel
Sprache:	eng
Schlagworte:	2,6‐diisopropylphenol 6-diisopropylphenol Activation Anesthesia Animals Apoptosis Apoptosis - drug effects Bones Caspase 3 Caspases - metabolism Cells, Cultured Enzyme Activation - drug effects hydrogen peroxide Hydrogen Peroxide - pharmacology Nitric oxide Nitrites - metabolism Nitroprusside - pharmacology Osteoblasts Osteoblasts - cytology Osteoblasts - drug effects Osteoblasts - enzymology Oxidative Stress Propofol - pharmacology Rats Rats, Wistar Reactive Oxygen Species - metabolism Sodium Viability
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