Proteomic characterization of inter-alpha inhibitor proteins from human plasma

Inter‐alpha inhibitor proteins (IaIp) are a family of structurally related serine protease inhibitors found in relatively high concentrations in human plasma. Recent studies have implicated a role for IaIp in sepsis, and have demonstrated their potential as biomarkers in sepsis and cancer. For chara...

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Veröffentlicht in:	Proteomics (Weinheim) 2006-05, Vol.6 (9), p.2874-2885
Hauptverfasser:	Josic, Djuro, Brown, Mari Kino, Huang, Feilei, Lim, Yow-Pin, Rucevic, Marijana, Clifton, James G., Hixson, Douglas C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha-Globulins - analysis Alpha-Globulins - isolation & purification Amino Acid Sequence Analytical, structural and metabolic biochemistry Biological and medical sciences Biomarkers Diagnostic and therapeutic agents Fundamental and applied biological sciences. Psychology Gas Chromatography-Mass Spectrometry Humans Inter-alpha inhibitor proteins Membrane Glycoproteins - blood Membrane Glycoproteins - isolation & purification Miscellaneous Molecular Sequence Data Plasma - chemistry Proteins Proteomic characterization Proteomics Serine Proteinase Inhibitors - blood Serine Proteinase Inhibitors - isolation & purification Spectrometry, Mass, Electrospray Ionization Trypsin Inhibitor, Kunitz Soybean - blood Trypsin Inhibitor, Kunitz Soybean - isolation & purification
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