RNA metabolism and dysmyelination in schizophrenia

Decreased expression of a subset of oligodendrocyte and myelin-related genes is the most consistent finding among gene expression studies of postmortem brain tissue from subjects with schizophrenia (SCZ), although heritable variants have yet to be found that can explain the bulk of this data. Howeve...

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Veröffentlicht in:	Neuroscience and biobehavioral reviews 2006, Vol.30 (4), p.551-561
Hauptverfasser:	McInnes, L. Alison, Lauriat, Tara L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult and adolescent clinical studies Animals Biological and medical sciences Brain - metabolism Brain - pathology Brain - physiopathology Demyelinating Diseases Gene expression Gene Expression Regulation Humans Medical sciences Myelin Oligodendrocytes Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Quaking RNA - metabolism RNA-Binding Proteins - metabolism Schizophrenia Schizophrenia - genetics Schizophrenia - metabolism Schizophrenia - pathology Schizophrenia - physiopathology Splicing factors
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