C5L2 Is a Functional Receptor for Acylation-stimulating Protein

C5L2 binds acylation-stimulating protein (ASP) with high affinity and is expressed in ASP-responsive cells. Functionality of C5L2 has not yet been demonstrated. Here we show that C5L2 is expressed in human subcutaneous and omental adipose tissue in both preadipocytes and adipocytes. In mice, C5L2 is...

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Veröffentlicht in:	The Journal of biological chemistry 2005-06, Vol.280 (25), p.23936-23944
Hauptverfasser:	Kalant, David, MacLaren, Robin, Cui, Wei, Samanta, Ratna, Monk, Peter N., Laporte, Stephane A., Cianflone, Katherine
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arrestin - metabolism Base Sequence Cell Line Complement C3a - metabolism DNA Primers DNA, Complementary Humans Mice Protein Binding Receptor, Anaphylatoxin C5a Receptors, Chemokine - genetics Receptors, Chemokine - metabolism RNA, Messenger - genetics
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